A comparison between the adverse event profiles of patients receiving palbociclib and abemaciclib: analysis of two real-world databases
Tatsuaki Takeda,
Shiho Sugimoto,
Jun Matsumoto
et al.
Abstract:Background: Palbociclib and abemaciclib are cyclin-dependent kinase (CDK) 4/6 inhibitors currently used to treat breast cancer. Although their therapeutic e cacies are considered comparable, differences of adverse event (AE) pro les between the two drugs remain unclear.Aim: We analysed two real-world databases, the World Health Organization's VigiBase and the Food and Drug Administration Adverse Event Reporting System (FAERS), to identify the differences in AE pro les between palbociclib and abemaciclib.Method… Show more
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