A comparison between intravaginal progestagen and melatonin implant treatments on the reproductive efficiency of ewes

To evaluate the efficacy of melatonin implants on increasing the production of lambs, a meta-analysis was performed based on the results of 139 experiments carried out in Spain and published in 56 scientific publications or conference proceedings. To assess the effects on fertility, the relative risk (RR) was calculated and, in the case of prolificacy and fecundity, the analysis was based on raw mean difference (D) and the standardized difference between means (d) and their corresponding confidence intervals. In addition, the experiments were stratified by the productive aptitude of the flocks, breed, time of year, and age. For fertility, the mean RR was 1.29, which indicated that the treatment with melatonin increased significantly (by 29%) the probability of pregnancy. For prolificacy, overall D was 0.08 (d = 0.9089); i.e., the groups treated with melatonin increased their litter size by 0.08 lambs/lambing relative to the control groups. Ultimately, treatment with melatonin increased fecundity significantly (0.25 extra lambs/ewe treated) (d = 6.3188), and this trend was evident in all of the stratified datasets. In all cases, there was significant (p < 0.001) heterogeneity and bias. In conclusion, in Spain, melatonin implants had a significant effect on the probability that a ewe became pregnant, increased the number of lambs born per lambing, which ultimately increased the number of lambs born per treated ewe. In addition to confirm the results of previous descriptive reviews in the scientific literature, the metaanalysis made use of a statistical tool that synthesizes and estimates more precisely the effect of this hormone on sheep reproduction.Additional key words: literature review; ovine reproduction; systematic review. Resumen Meta-análisis de la eficacia de los implantes de melatonina para incrementar los rendimientos reproductivos de la especie ovinaSe ha realizado un meta-análisis sobre la eficacia del uso de implantes de melatonina en ovino en España, analizando los resultados de 139 experiencias publicadas en 56 publicaciones o comunicaciones. Para la fertilidad se han calculado los riesgos relativos (RR) y para la prolificidad y fecundidad se han calculado la diferencia no estandarizada o bruta entre medias (D) y la diferencia estandarizada entre medias (d). Los resultados se han estratificado por aptitud productiva de los rebaños, raza, época del año y edad. Se han calculado los estadísticos de heterogeneidad y el posible sesgo entre publicaciones. Para la fertilidad, el RR medio fue 1,29, lo que significa que la melatonina incrementó de manera signif icativa las posibilidades de parto un 29%. Para la prolif icidad, la D global fue 0,08 (d = 0,9089), es decir, los grupos tratados incrementaron su prolificidad 0,08 corderos/parto. El tratamiento con melatonina aumentó de manera significativa la fecundidad, con 0,25 corderos extra producidos/oveja tratada (d = 6,3188). En todos los casos, la heterogeneidad y el sesgo calculados fueron significativos (p < 0,001). En conclusión, el metaanálisi...

show abstract

“…Requejo et al, 2005 Dairy AS 82. Gómez et al, 2006 Dairy Meat RA 88. Palacios et al, 2006 Meat LA 89.…”

Section: Quantitative Meta-analysismentioning

confidence: 99%

Meta-analysis of the efficacy of melatonin implants for improving reproductive performance in sheep

Palacín

Forcada

Abecia

1970

Span. j. agric. res.

View full text Add to dashboard Cite

show abstract

“…Prostaglandin F2α can be used for estrous synchronization and ovulation throughout the reproductive season (MENCHACA & RUBIANES, 2004). Conversely, during seasonal anestrous, the use of progesterone or synthetic progestagens associated with gonadotropins is required to sufficiently stimulate the follicular development to attain ovulation (GÓMEZ et al, 2006;HASHEMI et al, 2006;BARRETT et al, 2008). However, hormone delivery methods offer distinct advantages and/or limitations through their use.…”

Section: Introductionmentioning

confidence: 99%

Microbiological and functional evaluation of an alternative device (OB®) for estrous synchronization in ewes

Martins

Neto

et al. 2010

Cienc. Rural

View full text Add to dashboard Cite

show abstract

“…Among the possible alternatives for controlled breeding, one of the most widely used methods for the induction of oestrus is progestagen impregnated intravaginal sponges plus equine chorionic gonadotropin (eCG) treatments, the efficacy of which has been proven over time (Whitley and Jackson 2004; Gomez et al. 2006).…”

Section: Introductionmentioning

confidence: 99%

Effects of CIDR‐G and Melatonin Implants, and their Combination on the Efficacy of Oestrus Induction and Fertility of Kilis Goats

Çetin

Sagcan²,

Güngör

et al. 2009

Reprod Domestic Animals

View full text Add to dashboard Cite

The objective of this study was to compare the efficiency of oestrus induction protocols on Kilis dairy goats kept on a goat farm situated close to Kilis, Turkey. Eighty goats were assigned randomly into four groups of 20 animals each in a factorial arrangement: (i) untreated control (CON), (ii) melatonin implant (MEL), (iii) CIDR-G (CIDR) and (iv) melatonin implant plus CIDR-G (MC). Experiments were performed in mid-anoestrus season under natural photoperiod environment. The differences among treatment groups in oestrus response were significant. Oestrus response was higher in the MC group than in other groups (p < 0.05). A significant difference was observed in the time interval from cessation of treatment to the onset of oestrus among treatments. The CIDR-G treatment reduced intervals from buck introduction to oestrus. The time to onset of oestrus in both the MC and CIDR groups was significantly shorter, compared with the MEL and CON groups (p < 0.05). The number of does kidding and fertility were not different among treatment groups (p > 0.05). Fecundity was similar among goats in all groups. Prolificacy and twining rates showed similar trends as fecundity rates, with no differences (p > 0.05) between treatments. The results of this study showed that oestrus in Kilis does can be effectively induced by using melatonin and CIDR combined treatment, and fertility will not be adversely affected. However, this treatment did not improve fecundity, prolificacy and twining rates.

show abstract

A comparison between intravaginal progestagen and melatonin implant treatments on the reproductive efficiency of ewes

Cited by 24 publications

References 6 publications

Meta-analysis of the efficacy of melatonin implants for improving reproductive performance in sheep

Meta-analysis of the efficacy of melatonin implants for improving reproductive performance in sheep

Microbiological and functional evaluation of an alternative device (OB®) for estrous synchronization in ewes

Effects of CIDR‐G and Melatonin Implants, and their Combination on the Efficacy of Oestrus Induction and Fertility of Kilis Goats

Contact Info

Product

Resources

About