We compare using a prospective data collection the likelihood of infection and short-term revision in inflatable penile prosthesis (IPP) placements when using AMS 700 TM CX series versus Coloplast Titan®. The study included the first-time IPP implantations using both implants performed between January 2017 and December 2019. The surgeon alternated the implants every other week, and the patients were divided into two cohorts based on implant company for comparison and study. Data were collected on patient demographics, implant characteristics, perioperative features, and complications. Follow-up was carried out at 6 weeks, 3 months, and then annually. A total of 542 patients underwent IPP implantations during the two years, 301 (56%) were performed using AMS 700TMCX and 241 (44%) using Coloplast Titan®. There was only one (0.18%) case complicated by infection. Seven cases (1.3%) required revision, five had been done using AMS 700TM CX implants. Overall, the most common reason for revision was tube fracture (n=3). Diabetes, case time, reservoir type, and reservoir location were not significant prognostic factors for revision (p>0.05). We concluded that regarding manufacturing companies the risk of infection is not affected. Diabetes and drain placement for three days did not increase the risk of infection or overall revision.