A Comparing of Tp-Te Interval and Tp-Te/Qt Ratio in Patients with Preserved, Mid-Range and Reduced Ejection Fraction Heart Failure

Abstract

BACKGROUND: Heart failure (HF) is classified in three class: HF with preserved EF (HFpEF); normal or LVEF ≥ 50%, HF with reduced EF (HFrEF); LEVF < 40% and newly HF mid-range EF (HFmrEF); LVEF 40-49%. On Electrocardiography (ECG) T wave, Tpeak-Tend (Tp-Te) interval reflects transmural dispersion of repolarisation (TDR) which of these indexes have been proposed as predictors of risk for ventricular arrhythmia (VA) in many cardiac diseases.
 AIM: Aim of this study to asses these indices of TDR among three HF class.
 METHODS: Total of 192 patients were included in this study.
 RESULTS: Many of indices like Tp-Te, Tp-Te/QT wasn’t different between groups (P > 0.05). But mean Q-Tpeak (QTp), S-Tend (S-Te) and S-Tpeak (S-Tp) were found significantly different between groups (P < 0.05). Again S-Te was found different according to having fragmented QRS (fQRS) on ECG (P = 0.031). Comparing to mitral inflow E/A parameters showed significant differences for Tp-Te, Tp-Tec, Tp-Te/QT, Tp-Te/QTc and Tp-Tec/QTc parameters. Finally, we found correlations between S-Te and white blood cell (WBC) (r = - 0.171; P = 0.037) and S-Tp and WBC (r = - 0.170; P = 0.038) and between S-Te and fQRS (r = 0.158; P = 0.031).
 CONCLUSIONS: We didn’t find differences for many of indices of TDR like Tp-Te interval between groups except QTp, S-Te, S-Tp intervals. Also, S-Te and fQRS showed significant correlation. For prediction of ventricular arrhythmia and cardiovascular death newer indexes on ECG are needed to be established in the future which will make us facilitate to distinguish high risk patients.

Tpeak‐Tend ECG Marker in Obesity and Cardiovascular Diseases: A Comprehensive Review

“…It was also found that in patients with heart failure with a reduced ejection fraction (HFrEF), mean Tp-e and its standard deviation were higher than in those with heart failure with preserved ejection fraction (HFpEF) [ 82 ]. However, Son et al found no difference in Tp-e and Tp-e/QT ratio based on ejection fraction in three groups of heart failure patients (preserved, midrange, and reduced ejection fraction) [ 86 ].…”

Electrocardiography Predictive Value on Coronary Slow Flow Phenomenon

“…26 Tend corrected independent predictive factors on the risk of the incidence of sudden cardiac arrest, in which the value of> 90 ms had a significant correlation with the incidence of sudden cardiac arrest. [28][29][30] Some studies also studied duration TpeakT-late in conditions of myocardial infarction or ischemia. Conlon and colleagues found an increase in the duration ofT-thepeakTfinal in patients with coronary artery ataxia.…”