A Comparative Study to Evaluate the Efficacy of Oral Lactoferrin Fortified Bovine Colostrum with Oral Iron in the Treatment of Iron Deficiency Anemia

Ramakrishnan, Taruni; Sivaraman, Malar; Dutta, Trayambak; Ramasamy, Dhanasekar K

doi:10.5530/ijmedph.2018.2.15

Cited by 4 publications

(3 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean rises in Hb and serum iron concentration in their study were higher than those recorded in our study and this can be explained by higher doses of LF used in their study. 11 Similar results were also detected among Indian females aged 18 to 21 years, 12 where a significant increase of Hb level and serum iron was reported in cases that received LF fortified bovine colostrum once daily for 30 days and in cases that received combined therapy. The data from our study showed a significant increase in RBCs and HCT values posttherapy in group I and group III compared with group II.…”

Section: Discussionsupporting

confidence: 65%

See 1 more Smart Citation

Lactoferrin Efficacy versus Ferrous Sulfate in Treatment of Children with Iron Deficiency Anemia

El-Asheer

Ahmed

Hafez

et al. 2021

Journal of Child Science

View full text Add to dashboard Cite

Lactoferrin (LF) is an iron-binding globular glycoprotein that is structurally and chemically similar to serum transferrin. Many studies have been done to evaluate the effect of oral LF administration on iron deficiency anemia (IDA) with controversial results. This study was designed to compare the efficacy of LF versus oral ferrous sulfate (OFS) therapy in the treatment of children with IDA. A significant increase in mean hemoglobin and serum iron concentrations was noted in the group that received oral bovine LF (11.06 ± 0.96 and 42.79 ± 6.14, respectively) versus the group that received OFS (10.24 ± 0.57 and 28.94 ± 5.05, respectively, with p < 0.001 for each) after 30 days of the treatment with fewer side effects (9.3 vs. 33.3% with p = 0.043). Oral bovine LF is a more effective and safer alternative in treating iron deficiency and IDA compared with OFS with clinical benefits of fewer side effects and better patient compliance.

show abstract

Section: Discussionsupporting

confidence: 65%

“…Taruni also reported the same results as ours. 12 He found that LF was well tolerated with little side effects.…”

Section: Discussionmentioning

confidence: 99%

Lactoferrin Efficacy versus Ferrous Sulfate in Treatment of Children with Iron Deficiency Anemia

El-Asheer

Ahmed

Hafez

et al. 2021

Journal of Child Science

View full text Add to dashboard Cite

show abstract

“…According to Lepanto et al [ 106 ], milk-derived LF has the potential to chelate two ferric ions per molecule and can be seen as a natural anti-inflammatory substance that has the potential to modulate ferroportin and hepcidin synthesis by the downregulation of interleukin-6. Supporting the study of Lepanto et al [ 106 ], the potential of bovine LF in the treatment of Fe-deficiency anemia was also reported by Taruni et al [ 107 ]. El-Khawaga and Abdelmaksoud [ 108 ] stated that the LF can be an excellent alternative in the treatment of Fe-deficiency in school-going children.…”

Section: Current Evidence Of Therapeutic Use Of Bcsupporting

confidence: 74%

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

et al. 2022

View full text Add to dashboard Cite

Bovine colostrum (BC) is the initial mammary secretion after parturition, which is nature’s bountiful source consisting of nutritional and bioactive components present in a highly concentrated low-volume format. All mammalian newborns require colostrum to enhance physiological processes such as lifelong immunity, gastrointestinal development, and resistance to microbial infections. The genetic, environmental, and processing methods can all have an impact on the biochemical contents of BC and its supplements. BC and its derivatives have been intensively researched for their potential use in functional foods, medicines, and animal feed. Evidence from clinical studies suggests that BC products are well-tolerated, nontoxic, and safe for human ingestion. Functional foods, feed, and pharmaceutical formulations based on bovine colostrum are playing noteworthy roles in the development of innovative products for promoting health and the prevention of chronic illnesses. This systematic review sheds light on recent research on (a) the effects of processing techniques on BC components, (b) emerging techniques used in the isolation and identification of novel components, (c) BC-based functional foods for human consumption and animal feed supplements, and (d) the role of BC in current drug delivery, as well as future recommendations.

show abstract

Insights into protein-curcumin interactions: Kinetics and thermodynamics of curcumin and lactoferrin binding

et al. 2020

View full text Add to dashboard Cite

A Comparative Study to Evaluate the Efficacy of Oral Lactoferrin Fortified Bovine Colostrum with Oral Iron in the Treatment of Iron Deficiency Anemia

Cited by 4 publications

References 16 publications

Lactoferrin Efficacy versus Ferrous Sulfate in Treatment of Children with Iron Deficiency Anemia

Lactoferrin Efficacy versus Ferrous Sulfate in Treatment of Children with Iron Deficiency Anemia

Insights into the Research Trends on Bovine Colostrum: Beneficial Health Perspectives with Special Reference to Manufacturing of Functional Foods and Feed Supplements

Insights into protein-curcumin interactions: Kinetics and thermodynamics of curcumin and lactoferrin binding

Contact Info

Product

Resources

About