A comparative study on the effect of Pandughnivati and Dhatrilauhavati in the management of Garbhinipandu (Iron Deficiency Anemia)

Rupapara, Amit V; Donga, Shilpa B; Dei, Laxmipriya

doi:10.4103/0974-8520.123120

Cited by 7 publications

(7 citation statements)

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“…In this study, the increased serum iron and decreased TIBC in amloki and iron supplemented group in comparison to only iron supplemented group agree to others 11,20,21 .…”

Section: Discussionsupporting

confidence: 92%

Effect of Emblica Officinalis (amloki) on iron status in pregnant women with iron deficiency anaemia

Akter

Akhter

2019

J Bangladesh Soc Physiol

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Background: Common clinical practice of prescribing Iron supplementation for Iron deficiency anemia (IDA) in pregnancy is associated with a number of side effects. Emblica officinalis (amloki) is a well known dietary supplement used by traditional practitioners to treat anemia. Objective: To evaluate the effects of oral supplementation of Emblica officinalis on iron status in pregnant women with IDA. Methods: This prospective interventional study was carried out in the Department of Physiology, Dhaka Medical College (DMC), Dhaka from July 2016 to June 2017 on 43 pregnant women aged 18 to 36 years between 13th to 20th weeks of gestation with IDA. They were recruited from the Out-patient department of Obstetrics and Gynaecology, DMC Hospital. Among them 24 were supplemented with amloki and iron (IAS) and 19 women received only iron supplementation (IS). Study variables were estimated at the baseline and after 45 days of supplementation. Serum iron, ferritin and Total iron binding capacity (TIBC) were estimated following standard laboratory methods. Data were expressed as mean ± SD. Paired and Unpaired Student’s t-test were used for statistical analysis. Results: Serum iron levels were significantly higher (p<0.001) and serum TIBC were significantly lower (p<0.001) in both groups after supplementation compared to their baseline value. But post supplementation serum ferritin level was significantly higher (p<0.01) only in IAS group compared to that of the baseline. Again, after intervention, serum iron level was significantly higher (p<0.05) and serum TIBC was significantly lower (p<0.01) in IAS group when compared with those of IS group. Conclusions: Data concluded that oral Emblica officinalis supplement along with iron was more effective than only iron supplementation to improve serum iron status in pregnant women with IDA. J Bangladesh Soc Physiol. 2019, June; 14(1): 1-6

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“…In this study, the increased serum iron and decreased TIBC in amloki and iron supplemented group in comparison to only iron supplemented group agree to others 11,20,21 .…”

Section: Discussionsupporting

confidence: 92%

Effect of Emblica Officinalis (amloki) on iron status in pregnant women with iron deficiency anaemia

Akter

Akhter

2019

J Bangladesh Soc Physiol

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“…Lauha Bhasma and Mandura Bhasma are effective in Pandu Roga . On the basis of Pandughna (antianemic), Prinana (nourishing), Raktaprasadana (blood toner) properties and previous reports in Garbhini Pandu ,[ 5 ] Dhatri Lauha was selected in this study. Punarnava Mandura is successfully used by Ayurvedic physicians for the management of all types of Pandu .…”

Section: Introductionmentioning

confidence: 99%

Clinical efficacy of Punarnava Mandura and Dhatri Lauha in the management of Garbhini Pandu (anemia in pregnancy)

Khandelwal

Donga

Dei

2015

AYU

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Introduction:India is one of the countries with high prevalence of anemia during pregnancy. Anemia in pregnancy is multifactorial. Iron deficiency anemia is the most common conditions in a pregnant woman. As per ayurvedic classics, this condition occurs due to improper Rasa Dhatu in mother and continuously increasing fetal demands and is considered as Rasa Pradoshajavikara. A large number of Lauha preparations have been used widely for centuries to cure Anemia.Aim:To evaluate efficacy of Punarnava Mandura and Dhatri Lauha on Garbhini Pandu.Materials and Methods:A total 24 pregnant women with symptoms of Garbhini Pandu were randomly divided into two groups (A and B). In Group A (n = 15) Punarnava Mandura, two tablets (each of 500 mg) thrice a day with one cup (100 ml) of buttermilk and in Group B (n = 9) Dhatri Lauha, two tablets (each of 500 mg) thrice a day with luke warm water were administered for 90 days. The assessment was done with subjective parameters such as pallor, general weakness, dyspnea, etc., and objective parameters such as hematological parameters. Results were statistically analyzed using Student's t-test.Results:The results revealed that overall clinical improvement was better in Group A when compared to Group B. Hemoglobin was increased in patients of Group A, which was statistically significant. No adverse drug reaction was observed during the treatment period.Conclusion:Punarnava Mandura is more effective on Garbhini Pandu in comparison to Dhatri Lauha.

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“…[ 19 20 21 ] In these three studies, two different drugs have been studied for their clinical efficacy against anemia among pregnant women which includes Dhatrilauha Vati [ 20 21 22 ] and Pandughni Vati . [ 19 ] Anemia is one of the most common complications of pregnancy and contributes directly or indirectly to 20% of deaths in third world countries. [ 22 ] In Ayurveda, anemia during pregnancy is termed as Garbhini Pandu and is primarily caused due to vitiation Rasa Dhatu (one of the seven basic body structure described in Ayurveda).…”

Section: Discussionmentioning

confidence: 99%

“…The cumulative effects of all the ingredients leads to the correction of metabolism, iron absorption and improved blood formation, thereby correction of anemia. [ 19 ]…”

Section: Discussionmentioning

confidence: 99%

Ayurvedic preparations for the management of Iron Deficiency Anemia: A systematic review

Samal

2016

AYU

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Iron deficiency anemia (IDA) is a global public health crisis, so also in India. As per the World Health Organization's report, half of the total anemia is IDA. Ayurveda offers several formulations for the management of IDA. Given in this context, a systematic review was carried out to understand the role of Ayurvedic formulations for the management of IDA. For this purpose, articles were obtained from PubMed and through hand search process. Of the 37 articles identified, 10 articles were finally selected for the review. Of the 10 studies identified, 3 studies were (n = 10) exclusively focused on pregnant women, 2 studies (n = 10) were exclusively focused on pediatric age group, 1 study (n = 10) was exclusively focused on geriatric anemia and 4 studies (n = 10) were focused on general population. The response of most of the Ayurvedic formulations was better than Allopathic formulations and there was no untoward effect as observed with iron salts. Statistically significant results were obtained in favor of most of the Ayurvedic formulations in subjective and hematological parameters. Among six different formulations, Sarva-Jvara-Hara Lauha is suggested as the drug of choice for IDA as the Hb regeneration with this drug is highest- 0.16 g/dl/day, as reported by one of the studies. In addition, Punarnavadi Mandura is currently used as an anemia correcting agent at the community level promoted by the National Rural Health Mission and is included in the Accredited Social Health Activist's drugs kit. As most of these Ayurvedic formulations are found effective against IDA, their usage should be fostered at all level in addition to modern allopathic medicines.

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A comparative study on the effect of Pandughnivati and Dhatrilauhavati in the management of Garbhinipandu (Iron Deficiency Anemia)

Cited by 7 publications

References 1 publication

Effect of Emblica Officinalis (amloki) on iron status in pregnant women with iron deficiency anaemia

Effect of Emblica Officinalis (amloki) on iron status in pregnant women with iron deficiency anaemia

Clinical efficacy of Punarnava Mandura and Dhatri Lauha in the management of Garbhini Pandu (anemia in pregnancy)

Ayurvedic preparations for the management of Iron Deficiency Anemia: A systematic review

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