A Comparative Study on Phytochemical Fingerprint of Two Diverse Phaseolus vulgarisvar. Tondino del Tavo and Cannellino Bio Extracts

Abstract

Common bean (Phaseolus vulgaris) represents one of the most famous foods with antiobesity activity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidaemia. In this work, two Italian varieties of common bean, i.e., Tondino del Tavo and Cannellino Bio, from the centre of Italy were studied to characterise their phenolic profile by HPLC-PDA in relation to different fractions after a straightforward extraction procedure. Antioxidant property and enzymatic inhibition power were also evaluated in order to delineate a possible biological profile. Results show a considerable phenolic content (0.79 and 1.1 µg/mg of 3-hydroxybenzoic acid for hexane extract of Tondino del Tavo and Cannellino Bio, respectively; 0.30 µg/mg p-coumaric acid for n-hexane extract of Tondino del Tavo) for both varieties, and a strong antioxidant activity according to the major phenolic concentration of the extracts. The anti-inflammatory activity of the decoction extracts was also investigated through a zymosan-induced edema formation assay, revealing a moderate ability for both of them. These preliminary data prompt us to further explore the nutrient components of these two varieties in the future.

Phytochemical Profiling, Biological Activities and In Silico Virtual Screening of Bioactive Compounds of Trichodesma Indicum (L) R. Br. Extracts

“…By performing different antioxidant assays such as ABTS, DPPH, and H2O2, the best antioxidant results were examined based on their comparative effectiveness. It may be due to the nature of these radicals that the apparent differences exist (the ABTS assay is assumed to be both hydrophilic and lipophilic antioxidant systems, while DPPH is only for hydrophobic systems) [5] . Hence, various biological antioxidant assays were conducted to test the efficacy of biological active compounds found in chloroform and ethyl acetate fractions by comparing the results of DPPH, ABTS, H2O2 free radical scavenging activity upon the basis of the compounds nature.…”

“…and lipophilic antioxidant systems, while DPPH is only for hydrophobic systems). [5] Hence, various biological antioxidant assays were conducted to test the efficacy of biological active compounds found in chloroform and ethyl acetate fractions by comparing the results of DPPH, ABTS, H2O2 free radical scavenging activity upon the basis of the compounds nature.…”

“…Several extracts, such as those derived from common beans, have shown some positive effects against metabolic syndrome. Observations indicate that the extract has the capacity to inhibit Amylase, thus reducing the absorption of carbohydrates by the body, which can be reflected in a decrease in body weight, glucose levels, triglycerides, and cholesterol levels [5] . These extracts are the main source of secondary metabolites.…”

Chemical Composition and Antioxidant, Antimicrobial, and Anti-Inflammatory Properties of Origanum compactum Benth Essential Oils from Two Regions: In Vitro and In Vivo Evidence and In Silico Molecular Investigations

“…Enhancing beer with various flavonoids and other dietary supplements such as taurine, resveratrol, and caffeine has increased its nutritional value [ 14 ]. The common bean ( Phaseolus vulgaris ) has been shown to have significant anti-obesity potential due to its high phenolic content and antioxidant effects, exhibiting significant effectiveness against fat formation and insulin resistance [ 15 ]. According to recent studies, many food wastes, especially the byproducts of vegetables and fruits, are an excellent source of bioactive substances that may be isolated and added to food as natural food additives or used as complex matrices to create nutraceuticals and functional meals [ 16 ].…”

Antioxidant and Anti-Inflammatory Activities of Sargassum macrocarpum Extracts

“…Although various biological activities have been identified in various Sargassum species, little is known about the properties of S. macrocarpum . According to a previous study, the two Italian varieties of common bean showed a potent antioxidant activity and anti-inflammatory activity depending on the concentration of the major phenols in them [ 19 ]. In addition, another study reported that the extracts of A. macrostachyum , H. portulacoids , and S. europaea showed different enzyme inhibition effects, with different total phenols and flavonoids depending on the extraction method [ 20 ].…”