A comparative study on ingredient and efficiency difference between fresh and steamed Gastrodia elata Blume: An herbal material to a novel functional food

Ma, Ji; Deng, Yang; Liu, Qiuyan; An, Jing; Li, Maoru; Song, Nali; Zhang, Ju; Cheng, Lijun; Ma, Ke

doi:10.1016/j.jff.2021.104512

Cited by 17 publications

(14 citation statements)

References 17 publications

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“…The chemical ingredients of fresh GE and AGE were detected in accordance with previous studies ( Li et al, 2019 ; Ma et al, 2021 ).…”

Section: Methodssupporting

confidence: 89%

“…As described in our previous study ( Ma et al, 2021 ), all the fresh GE samples were obtained from Xiaocaoba planting base in Zhaotong (Yunnan province, China), and were authenticated by Prof. Qin Meng (Yunnan institute of food and drug control, Kunming, China). The voucher sample (Authentication No.…”

Section: Methodsmentioning

confidence: 99%

“…The phenobarbital-induce sleep mice model was performed according to our previous study ( Ma et al, 2021 ). The rats were randomly divided into four groups: control, estazolam, fresh GE, and alcohol-steamed GE (AGE).…”

Section: Methodsmentioning

confidence: 99%

“…All animals were sacrificed after the behavioral test and their serum and whole brain tissue were collected for stepping detection. Serum samples (eight samples per group) were prepared and detected by the method mentioned in our previous study ( Ma et al, 2021 ).…”

Section: Methodsmentioning

confidence: 99%

“…Historically, GE was commonly processed with yellow rice wine, refined honey, wheat bran, and even ginger juice ( Yang et al, 2018 ), but now it is officially recommended to be steamed by using water and then dried to obtain high-quality pieces according to Chinese pharmacopoeia ( Commission 2015 ). Our previous study indicated that more effective ingredients were extracted after water steaming, and a distinct better bio-activity was found in the water steamed GE group rather than the fresh GE group ( Ma et al, 2021 ). Gastrodin a major component of GE, easily soluble in wine and processing GE with wine could not only fully dissolve its effective components, but also showed a better effect.…”

Section: Introductionmentioning

confidence: 99%

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A novel alcohol steamed preparation from Gastrodia elata Blume: Pharmacological assessment of a functional food

Cheng

Wang

et al. 2023

Front. Pharmacol.

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Rhizoma Gastrodia (Orchidaceae; Gastrodia elata Blume), the rhizome of Gastrodia elata Blume (GE), is traditionally used as both a medicinal and functional food, with proven efficacy in treating mental disorders. In traditional processing, GE is washed, steamed with water, dried, and sliced. In this study, a novel processing technology-alcohol steamed GE (AGE) was proposed as an alternative. Totally, 17 compounds were identified in fresh GE and AGE. Compared with fresh GE, the relative content of parishin A and parishin E decreased after alcohol steaming, whereas gastrodin (GAS), p-hydroxylbenzyl alcohol (HBA), Parishin B, and Parishin C were increased. Additionally, the pentobarbital-induced sleep mice model and Chronic Restraint Stress (CRS) model were applied to evaluate the pharmacological effects of fresh GE and steamed GE, and both fresh and steamed GE showed an intensive hypnotic and anti-anxiety effect. Furthermore, the anti-anxiety mechanism based on serum metabolic was investigated and the tryptophan metabolic pathway was considered the response to the anti-anxiety effect of GE. Although the optimization of the processing technology of AGE still needs to be further explored, the current results have provided new thoughts for the processing technology and clinical application of GE.

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“…The chemical ingredients of fresh GE and AGE were detected in accordance with previous studies ( Li et al, 2019 ; Ma et al, 2021 ).…”

Section: Methodssupporting

confidence: 89%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%