A B S T R A C TObjective: This study aimed to determine the prevalence and factors associated with poor sleep quality among medical students at a Nigerian university. Materials and Methods: In a cross sectional survey, the sleep quality of students (n=255) was assessed using the Pittsburgh Sleep Quality Index (PSQI). In addition to obtaining sociodemographic data, history of adverse childhood experiences and drug use, measures assessing daytime sleepiness, fatigue and psychiatric morbidity were also administered. Results: Almost a third (32.5%) of medical students reported poor quality sleep. The presence of a chronic illness (OR: 5.10, 95% CI: 1.53-17.11, P<0.02), adverse childhood experience (OR: 1.73, 95% CI: 0.98-3.02, P<0.05) and irregular sleep schedule (OR: 4.78, 95% CI: 2.65-3.02, P<0.01) signifi cantly predicted poor sleep quality. Conclusion: Poor quality of sleep is common among medical students, and is associated with predisposing and several modifi able factors. Strategies to improve sleep quality are suggested.