A comparative study of the efficacy of topical negative pressure moist dressings and conventional moist dressings in chronic wounds

Abstract

Aim: To assess the efÞ cacy of topical negative pressure moist wound dressing as compared to conventional moist wound dressings in improving the healing process in chronic wounds and to prove that negative pressure dressings can be used as a much better treatment option in the management of chronic wounds. Materials and Methods: This is a prospective comparative study of data from 112 patients with chronic wounds, of which 56 patients underwent topical negative pressure dressings (17 diabetic, 10 pressure sores, nine ischemic, two varicose, 10 post-infective raw areas and eight traumatic -six had bone exposed, two orthopaedic prosthesis exposed). The remaining 56 patients underwent conventional moist dressings (20 diabetic, two ischemic, 15 pressure sores, three varicose, eight post-infective raw areas and eight traumatic -Þ ve had bone exposed, three orthopaedic prosthesis exposed). The results were compared after 10 days. The variables compared were, rate of granulation tissue formation as a percentage of ulcer area covered, skin graft take up as the percentage of ulcer surface area and duration of hospital stay. The variables were compared using Unpaired Student's t test. A "P" value <0.05 was considered signiÞ cant. Results: Out of 56 patients who underwent topical negative pressure dressings, six (10.71%) were failures, due to failure in maintaining topical negative pressure due to defective sealing technique; these were included into the study group. After 10 days, the mean rate of granulation tissue formation was 71.43% of ulcer surface area. All these 56 cases underwent split-thickness skin grafting. The mean graft take-up was 79.29%. The mean hospital stay was 32.64 days. In the remaining 56 patients, the mean rate of granulation tissue formation was 52.85% of ulcer surface area. The mean graft take-up was only 60.45% of the total ulcer surface area. The mean hospital stay was 60.45 days. Conclusion: To conclude, topical negative pressure dressings help in faster healing of chronic wounds and better graft take-up and reduce hospital stay of these patients.

Comparative analysis of the efficacy of topical negative pressure dressing with conventional wound dressing in wound healing

“…In Tauro et al also the main etiology was diabetic ulcer but next most common cause was pressure ulcer and in our present study there was no ischemic ulcer and pressure ulcer. 10 Prabhdeep SN et al, study in 15 diabetic foot ulcers, received vacuum dressing percentage of mean reduction of wound of 16.14% which is lesser compare to present study, and mean age is higher (61.33 years) compare to present study (43.56 years). 12 Nather et al, done study of vacuum dressing in 5 diabetic foot ulcers, shows higher percentage of reduction in wound size (32.8 %) compare to present study (25.57%).…”

“…In present study split skin graft was done only in 19 patients in study group and 11 patients in control group. 10,11 There is significant increase in wound bed score in the study group (mean difference was 9.60±2.16) where as in the control group there was not much increase in wound bed score (mean difference was 5.12±1.99) (p-valve 0.00001) which is statistically significant. Even the percentage of granulation tissue formation and the percentage of graft take up is higher in the study group compared to the control group, which is statistically significant (p value <0.001) in both variables.…”

“…25. 10,11 Patients in our present study were suffering from ulcers of varied etiology, most common etiology was diabetic, next most common was infective etiology. In Tauro et al also the main etiology was diabetic ulcer but next most common cause was pressure ulcer and in our present study there was no ischemic ulcer and pressure ulcer.…”

An Easy Technique for Negative-Pressure Wound Therapy for Extremities Using Collagen Powder and Sterile Gloves

“…Compared with traditional wound care, NPWT is believed to work based on its ability to remove edema and exudates, reduce bacteria counts, increase granulation tissue and angiogenesis, and reverse tissue retraction at an open wound. The rate of granulation tissue formation and patient compliance was better with topical negative-pressure dressing as compared to the conventional dressing [3].…”

To compare the efficacy of topical negative pressure dressing with that of conventional moist wound dressings, in healing of wounds

“…5,6 In our present study split skin graft was done only in 19 patients in study group and 11 patients in control group. Patients in our present study were suffering from ulcers of varied etiology, most common etiology was diabetic, next most common was infective etiology.…”