A Comparative Study of The Effect of Demineralized Bone Matrix with and Without Low Level Laser Therapy on The Treatment of Periodontal Infra-Bony Defects (Randomized Clinical Trial)

Abstract

Objective: This study aimed at comparing clinically and radiographically the therapeutic effect of low level laser therapy and demineralized bone matrix, used in management of periodontal intrabony defect. Subjects and methods: Thirty two non-smoking patients aged between 28-51 years with severe chronic periodontitis participated in this randomized clinical study. Patients were randomly assigned into one of 2 groups (16 patients each): demineralized bone grafting alone of the intrabony defect, control group (Group I), demineralized bone grafting and the application of low level laser therapy (LLLT) (Group II). Clinical and radiographic parameters including plaque index, bleeding index, probing depth, clinical attachment level (CAL) and intrabony defect depth were reassessed at 6 months after surgery. Results: Specifically, LLLT treated sites (Group II) showed statistically significant differences regarding pocket depth and CAL compared with Group I. Intrabony defect depth was significantly reduced for LLLT group compared to that of Group I control. Conclusion: The use of LLLT as an adjunct with demineralized bone matrix (DBM) in the treatment of intrabony defects was more significant in improving the probing depth, CAL and intrabony defect depth than using DBM alone. Complete periodontal regeneration is unpredictable with any regenerative therapy currently used, so, periodontal bone grafts show

Comparative evaluation of the effectiveness of concentrated growth factor alone and in combination with diode laser application in the treatment of intrabony periodontal defects: A clinical and radiographic split-mouth study

“…However, the differences were statistically insignificant between the two experimental sites. Gamil et al 27 observed similar results in the management of intrabony defects where the defect depth was reduced from 5.4 ± 0.7 mm to 0.9 ± 0.5 mm at six months postoperatively in defects treated with LLLT and demineralized bone matrix than defects treated with demineralized bone matrix alone with a mean difference of 2.0 ± 0.4 mm, respectively. The results of the present study were similar to the study by Vaid et al, 25 where the defect area was reduced from 10.55 mm to 6.35 mm at six months postoperatively in the CGF group.Thalaimalai et al 28 also observed 2.44 mm of radiographic bone fill in patients treated with simplified papilla preservation flap (SPPF) with LLLT + PRF than patients treated with SPPF + PRF alone at the end of six months, similar to the present study in the treatment of intrabony periodontal defects.…”