A comparative study of the effectiveness of the Rinkel method and the current standard method of immunotherapy for ragweed pollen hay fever

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008*

“…• mixtures of related, cross-reacting allergen vaccines such as grass-pollen vaccines, deciduous-tree pollen vaccines, related ragweed pollen vaccines and related mite vaccines or • mixtures of other allergen vaccines provided that stability data (1641) (1645)(1646)(1647) and high doses of allergen vaccines may induce a high and unacceptable rate of systemic reactions (1647). Thus, optimal doses using vaccines labeled either in biological units or in mass of major allergens have been proposed (1193).…”

Immunotherapy as an effective tool in allergy treatment

“…Most immunotherapy studies investigated the efficacy of pollen allergies. These studies can be subdivided into 13 studies (5,7,9,11,12,15,17,19,22,32,35,36,39) investigating ragweed allergy (nine showing clinically relevant efficacy, i.e., symptom/medication scores diminished by >30% in the actively treated). Fifteen studies investigated the efficacy of immunotherapy in grass-pollen allergy (8,13,16,18,20,21,23,25,30,34,37,38,40,44,47), of which 14 proved efficacy.…”

Recombinant allergens/ allergen standardization

“…Although successfully used throughout 90 years it has also been used in manners comparable with homeopathies [11], raising criticism and causing allergy treatment to develop in the direction of barely symptomatic drug treatment. Nevertheless, very recently performed clinical studies have revealed both a curing [12•] and a preventive effect.…”