1981
DOI: 10.1016/0006-8993(81)91015-5
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A comparative study of selective stimulation of raphe nuclei in the cat in inhibiting dorsal horn neuron responses to noxious stimulation

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Cited by 13 publications
(2 citation statements)
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“…The dorsal raphe nucleus (DRN) is enriched in serotonin (5-hydroxytryptamine; 5-HT) neurons that play a critical role in the regulation of pain and affect (Akil and Mayer, 1972;Dugué et al, 2014;Griffith and Gatipon, 1981;Horie et al, 1991;Mayer and Liebeskind, 1974;Oliveras et al, 1979). Pro-inflammatory stimuli can precipitate 5-HT neuronal degeneration, induce cfos expression, and alter 5-HT neuronal activity in the DRN (Brambilla et al, 2007;Hochstrasser et al, 2011a;Hollis et al, 2006;Manfridi et (which was not certified by peer review) is the author/funder.…”
Section: Introductionmentioning
confidence: 99%
“…The dorsal raphe nucleus (DRN) is enriched in serotonin (5-hydroxytryptamine; 5-HT) neurons that play a critical role in the regulation of pain and affect (Akil and Mayer, 1972;Dugué et al, 2014;Griffith and Gatipon, 1981;Horie et al, 1991;Mayer and Liebeskind, 1974;Oliveras et al, 1979). Pro-inflammatory stimuli can precipitate 5-HT neuronal degeneration, induce cfos expression, and alter 5-HT neuronal activity in the DRN (Brambilla et al, 2007;Hochstrasser et al, 2011a;Hollis et al, 2006;Manfridi et (which was not certified by peer review) is the author/funder.…”
Section: Introductionmentioning
confidence: 99%
“…The dorsal raphe nucleus (DRN) is enriched in serotonin (5-hydroxytryptamine; 5-HT) neurons that play a critical role in the regulation of pain and affect (Akil and Mayer, 1972;Dugué et al, 2014;Griffith and Gatipon, 1981;Horie et al, 1991;Mayer and Liebeskind, 1974;Oliveras et al, 1979). Pro-inflammatory stimuli can precipitate 5-HT neuronal degeneration, induce cfos expression, and alter 5-HT neuronal activity in the DRN (Brambilla et al, 2007;Hochstrasser et al, 2011a;Hollis et al, 2006;Manfridi et al, 2003), suggesting that chronic alcohol may promote hyperalgesia and negative affect by activating neuro-immune mechanisms in the DRN that ultimately perturb 5-HT neurotransmission.…”
Section: Introductionmentioning
confidence: 99%