2021
DOI: 10.21873/invivo.12274
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A Comparative Study of Pigmented and Non-pigmented Basal Cell Carcinoma in Reflectance Confocal Microscopy

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Cited by 5 publications
(2 citation statements)
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References 15 publications
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“…From the outset, we anticipated that establishing differences between these tumors by RCM would be difficult because they have architectural and cellular similarities, such as the presence of basaloid cell aggregates with peripheral palisade. 8 However, keratinocyte polarization, which was present in most cases of BCC, was not observed in the trichoepitheliomas, in which a pattern that approximated normal epidermis developed on the surface, including granular and prickly layers with well-defined cell contours, in a honeycomb pattern.…”
Section: Discussionmentioning
confidence: 93%
“…From the outset, we anticipated that establishing differences between these tumors by RCM would be difficult because they have architectural and cellular similarities, such as the presence of basaloid cell aggregates with peripheral palisade. 8 However, keratinocyte polarization, which was present in most cases of BCC, was not observed in the trichoepitheliomas, in which a pattern that approximated normal epidermis developed on the surface, including granular and prickly layers with well-defined cell contours, in a honeycomb pattern.…”
Section: Discussionmentioning
confidence: 93%
“…Dermoscopy revealed a pigmented pattern resembling leaf-like areas. To avoid unnecessary surgical removal, dynamic optical coherence tomography (D-OCT) and reflectance confocal microscopy (RCM) were performed, both showing tumor islands (1,2). Thanks to non-invasive imaging, a diagnosis of pigmented BCC was made, considering its indolent biologic behaviour, definitive surgery could be scheduled after delivery.…”
Section: Introductionmentioning
confidence: 99%