“…Uni-or multi-locular radiolucent lesions such as ameloblastoma (AB), in particular, and odontogenic keratocysts, which have now been officially reclassified as keratocystic odontogenic tumors (KOT) by the World Health Organization 1) , are very difficult to differentiate on panoramic radiographs 10) , although this does not apply to desmoplastic AB. Most previous articles focusing on the differential diagnosis of radiolucent jaw lesions on panoramic radiographs have analyzed individual radiographic elements in fragments, such as size, morphological characteristics, marginal conditions, lesion density, location with regard to adjacent tooth structures, radicular state of adjacent teeth, cortical involvement and other factors 2,6,[13][14][15] . However, both AB and KOT resemble each other in the image findings for these radiographic elements.…”