A Comparative Study of Ketofol (Ketamine and Propofol) With Propofol Alone for Recovery in Patients Undergoing Laparoscopic Cholecystectomy

Abstract

Background: To compare the recovery in ketofol (ketamine and propofol) with propofol alone for vas in patients undergoing laparoscopic cholecystectomy
 Methods: Prospective, randomized, double blinded controlled trial. After approval by the research ethics committee and written informed valid consent of the patients, the proposed study was carried out for a period of one year in 60 patients , in ASA-I and ASA-II patients, aged between 19 to 60 years of either sex, who were posted for laproscopic cholecystectomy surgery at Indira Gandhi Medical College, Shimla.
 Results: Recovery profile was statistically significant for two groups. In group P after stopping infusion ,mean time for eye opening was 8.27 ± 1.28 which was less than group K ( 12.53 ± 1.48). Mean time of response to verbal command in group P(8.4 ± 1.19) was less than group K (12.5 ± 1.46) and mean time of extubation in group P (9.5 ± 1.25) was also less than group K (14.33 ± 1.52).
 Conclusion- Patients of Group P after stopping of infusion took less time for eye opening, obeying verbal command and also less time for extubation in comparison to group K .
 Keywords: Recovery, Propofol, Ketamine