A comparative study of hematological profile on presentation in confirmed cases of malaria, dengue and leptospirosis

Vaidya, Meghna; Kawale, Juhi; Maheshkar, Parag Rajkumar; Kamble, Aniket Namdev

doi:10.18203/2320-6012.ijrms20180284

Cited by 2 publications

(3 citation statements)

References 11 publications

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“…11 Vaidya MS et al, study showed more than the double ratio of incidence of malaria in males compared to females. 12 In present study most commonly affected age group is 21-40, which contributes to 65% of total patients. The percentage of patients affected aged above 60 is 9%.…”

Section: Discussionmentioning

confidence: 64%

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

et al. 2020

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Background: Malaria is a major health problem in many parts of India and some parts of Andhra Pradesh is one of the endemic areas for malaria. The objective was to study clinical profile and outcome of malaria in both species and mixed infection.Methods: Present study was carried out on 100 patients admitted during the period of November 2016 - October 2018 in Narayana medical college and hospital, Nellore. Malaria confirmed by Peripheral thick and thin smear or Antigen Assay underwent detailed clinical history and physical examination. This was followed by monitoring the outcome of the patients with respect to morbidity and mortality.Results: Out Of the 100 patients 58 patients were from rural background, males were predominant, most common age group was 20-30 (34%) followed by 31-40 (31%). Out of 100 patients, 54 patients were falciparum,44 patients had vivax and two had mixed infection. All of the patients had fever followed by chills and rigors (75%), nausea and vomiting (59%), easy fatiguability (28%), pain abdomen (17), cough (14%) in both infections, altered sensorium was seen in only falciparum (20.3%). On clinical examination,70% of the patients had pallor, splenomegaly in 46%, icterus (23%), hepatomegaly (14%) and pedal edema in12 patients were observed. All 0f the patients were treated with appropriate antimalarial drugs for appropriate duration, and all were recovered without any mortality.Conclusions:Malaria is very common disease in our country especially in South India, which is one of the endemic areas. Severe malaria usually caused by the falciparum more than vivax, early diagnosis and treatment decreases the mortality and morbidity.

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Section: Discussionmentioning

confidence: 64%

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

et al. 2020

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“…In Vaidya MS et al, study it was about 27.3%. 11 Arevalo Herrera et al had 19.7% and Rathod SN et al, had 27.3% of anemia incidence in their studies. 12 The percentage of incidence of severe anemia (7gm/dl) in our present study is 20% most of which is due to falciparum infection malaria compared to vivax malaria.…”

Section: Discussionmentioning

confidence: 89%

“…73.01% of the patients with spleenomegaly had thrombocytopenia (Table 2). (11) and in mixed infection 100% (2). Lymphopaenia was observed in 13% ( 13) of total patients.…”

Section: Figure 1: Incidence Of Different Species Of Malariamentioning

confidence: 99%

Haematological profile and its outcome in different species of malaria: a two year study

et al. 2020

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Background: Malaria is a major health problem in many parts of India and some parts of Andhra Pradesh, which is also one of the endemic areas for malaria. Several factors have been attributed to increased morbidity and mortality in malaria especially with altered hematological and coagulation parameters playing an important role. The aim of present study was to study the hematological and coagulation abnormalities that correspond to severity and the final outcome.Methods: The present study was carried out on 100 patients admitted during the period of November 2016 to October 2018 at Narayana Medical College and hospital, Nellore. All of these patients were confirmed by Peripheral Smear or MPQBC or Antigen Assay followed by detailed clinical history, physical examination and investigated with hematological and coagulation parameters. Then subsequently required routine and special investigation which was followed by monitoring the outcome of the patients with respect to morbidity and mortality.Results: Out of 100 patients 20 patients had severe anemia (Hb% <7 gm%) and most of them patients were falciparum and mixed infection cases. Thrombocytopenia was observed in 63% of the patients and severe thrombocytopenia (<50,000 mm3) was seen in 12% of the patients. PT and APTT were increased in 18% and 13% of the cases respectively. BT was increased in 5% of the cases. None of the patients expired in this study.Conclusions: severe anemia is a poor prognostic factor and has adverse outcome. Thrombocytopenia, increased PT, APTT does not have any correlation to mortality.

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A comparative study of hematological profile on presentation in confirmed cases of malaria, dengue and leptospirosis

Cited by 2 publications

References 11 publications

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

Clinical profile of falciparum, vivax and mixed infections of malaria, from a tertiary care hospital, Coastal Andhra, India

Haematological profile and its outcome in different species of malaria: a two year study

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