A Comparative Study of Dexmedetomidine and Fentanyl as Adjuvants with Bupivacaine in Adductor Canal Block Regional Anesthesia in Total Knee Replacement Surgery

Naik, Sudhir M; Patil, Channabasava; Venkategowda, Chaitra; Reddy, Narasimha

doi:10.5005/jp-journals-10046-0156

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many scholars have endorsed propofol combined with low-dose fentanyl for intravenous anesthesia ( 8 , 9 ). Fentanyl, as an opioid receptor agonist, has a rapid onset of action, a short duration of action, and a strong analgesic effect without affecting the patient's normal breathing.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Analgesic Propofol/Esketamine and Propofol/Fentanyl for Painless Induced Abortion: A Randomized Clinical Trial

Xin¹,

Yan²,

Jin³

2022

BioMed Research International

View full text Add to dashboard Cite

Background. Patients have widely accepted abortion as a remedy for contraceptive failure all over the world. Esketamine is a new anesthetic, sedative, and analgesic drug. Fentanyl is an opioid receptor agonist and a commonly used sedative. It is necessary to choose appropriate sedative drugs for painless abortion. Methods. We selected 238 cases of painless induced abortion from January 2020 to January 2022. We collected surgical parameters, the performance of sedation, and postoperative scales with complications before and after the operation. SPSS 21.0 was used to analyze data. Results. Surgical indicators between intervention and control groups had no difference; the preoperative indicators including intraoperative bispectral index (BIS), systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse oxygen saturation (SpO2) had no difference between the two groups. But after surgery, experiment groups had a higher value than the control group in these four indicators. The incidence of postoperative complications including nausea and vomit had no significant difference while the experiment group had a lower r -value than the control group in hypotension, bradycardia, decreased oxygen saturation, and respiratory depression. The postoperative VAS score and Ramsay score in the experimental group were lower than those in the control group. Conclusion. Since esketamine had better sedation performance, reduce the risk of cardiovascular and respiratory depression during sedation, and reduce the pain scale compared with fentanyl, we supported that propofol/esketamine is a good choice for patients receiving a painless induced abortion, and it is a sedation plan worth promoting and further analysis.

show abstract

Section: Introductionmentioning

confidence: 99%