A comparative study of conjunctival autograft with fibrin glue or glueless sutureless conjunctival autograft after pterygium surgery

Abstract

Background: Conjunctival autografting after Pterygium excision can be done by fibrin glue or sutures but use of foreign material can cause discomfort and infection. Fibrin glue may cause hypersensitivity reaction and also have risk of viral transmission. To avoid these conjuctival autograft can be applied without suture or glue. Patient’s own blood act as a bioadhesive.Methods: We done a prospective randomized control study of 70 patients, 35 patients allocated in each group. Group A had conjunctival autograft with fibrin glue while group B had conjunctival autografting without glue or sutures.Results: In group A 31 and group B 26 patients had well placed conjunctival autograft while 4 in group A and 9 patients in group B had either displaced or dislodged graft. The results were statistically insignificant with P value of 0.219 and No complication was reported in any patient except recurrence. The 5 patients in group A and 6 in group B had recurrence which is not statistically significant.Conclusions: Graft stability is more with fibrin glue as compare to glueless and sutureless conjunctival autografting but using patients own blood as bioadhesive is safer and cost effective. The rate of recurrence is similar in both the groups.

Long Term Follow Up Results of Pterygium Excision with Conjunctival Autograft using Fibrin Glue: A Retrospective Study

“…de Wit et al 30 described another technique of sutureless and glueless technique of conjunctival autograft in a case series and concluded that it provides good cosmesis and no post-operative complications. This technique of sutureless and glueless technique was used by Jain et al 31 which demonstrated the rate of recurrence of pterygium to be same in sutureless and glueless conjunctival autograft and conjunctival autograft with glue but graft displacement and retraction were more in the former group, thus making fibrin glue usage for securing conjunctival autograft a more safe technique. However, the main disadvantage of fibrin glue is its cost.…”