A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Volga M Saini,
Ezgi Oner,
Mark Ward
et al.
Abstract:Circulating tumor cells (CTCs) have potential as diagnostic, prognostic and predictive biomarkers in solid tumors. Despite FDA approval of CTC devices in various cancers, their rarity and limited comparison between analysis methods hinder their clinical integration for lung cancer. This study aimed to evaluate five CTC isolation technologies using a standardized spike-in protocol: the CellMag ™ (EpCAM-based enrichment), EasySep ™ and RosetteSep ™ (blood cell depletion), and the Parsortix® PR1 and next generati… Show more
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