A Comparative Study of Antihy Aluronidase, Antistreptolysin “O,” Antistreptokinase, and Streptococcal Agglutination Titers in Patients With Rheumatic Fever, Acute Hemolytic Streptococcal Infections, Rheumatoid Arthritis and Non-Rheumatoid Forms of Arthritis 1

Quinn, Robert W.; Liao, Sung J.

doi:10.1172/jci102353

Cited by 36 publications

(6 citation statements)

References 26 publications

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“…The behavior of the latter three antibodies was similar to that observed in other studies (12)(13)(14)(15) Like the other streptococcal antibody studies, mean titers of ASDA were somewhat higher in acute rheumatic fever patients' sera than in the sera of patients with uncomplicated streptococcal infection. This tendency of the rheumatic host to show greater streptococcal antibody levels has been reported repeatedly (13).…”

Section: Discussionsupporting

confidence: 88%

Serum Inhibition of Streptococcal Diphosphopyridine Nucleotidase in Uncomplicated Streptococcal Pharyngitis and in Rheumatic Fever *

Bernhard¹,

Stollerman²

1959

J. Clin. Invest.

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Section: Discussionsupporting

confidence: 88%

Serum Inhibition of Streptococcal Diphosphopyridine Nucleotidase in Uncomplicated Streptococcal Pharyngitis and in Rheumatic Fever *

Bernhard¹,

Stollerman²

1959

J. Clin. Invest.

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“…For example, this has been shown to be true for antistreptolysin "0" (e.g. reference 21), anti-streptokinase (22), anti-hyaluronidase (23), antistreptococcal proteinase (24) and anti-desoxyribonuclease (25). Total gamma globulin levels in the sera of rheumatic patients also tend to be higher than those found in patients with uncomplicated streptococcal infections (26).…”

Section: Discussionmentioning

confidence: 95%

The Analysis of Streptococcal Infections

Halbert

Keatinge

1961

The Journal of Experimental Medicine

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It has been found by immunoelectrophoresis, that Group A streptococci release at least 20 distinct extracellular antigens in human tissues, as judged by naturally occurring antibodies present in normal pooled human gamma globulin. Several of these precipitin arcs have been identified with streptococcal antigens previously purified by electrophoresis and chromatography. Human gamma globulin, as well as several rheumatic fever sera, were shown to be remarkably potent in antistreptococcal antibodies, when compared to four horse antibody concentrates obtained by hyperimmunization with several streptococcal filtrates. A Group C streptococcal culture concentrate revealed 8 or 9 antigens for which corresponding antibodies were present in human gamma globulin.

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“…1). AIthough the level of ASOT titre does not correlate strongly with the severity of a streptococcal infection (5), patients with acute rheumatic fever tend to have higher titers compared to patients with simple streptococcal infections (12). The interval between onset of pharyngitis and development of neurological features is also in the range documented for acute rheumatic fever.…”

Section: Introductionmentioning

confidence: 99%

Acute Encephalomyelitis: Extending the Neurological Manifestations of Acute Rheumatic Fever?

Munn

Farrell²,

Cimolai³

1992

Neuropediatrics

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The clinical course of a five-year-old boy who developed meningeal irritation, encephalomyelitis, and optic neuritis four weeks after Streptococcus pyogenes pharyngitis is detailed. The patient responded to therapy with corticosteroids and recovered fully. Review of the literature reveals that a wide range of neurological disorders have been described in association with rheumatic fever. We suggest that disseminated encephalomyelitis in this child most probably was related to the streptococcal infection and that the spectrum of post-infectious neurological disorders associated with Streptococcus pyogenes may be broader than is currently appreciated.

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A Comparative Study of Antihy Aluronidase, Antistreptolysin “O,” Antistreptokinase, and Streptococcal Agglutination Titers in Patients With Rheumatic Fever, Acute Hemolytic Streptococcal Infections, Rheumatoid Arthritis and Non-Rheumatoid Forms of Arthritis 1

Cited by 36 publications

References 26 publications

Serum Inhibition of Streptococcal Diphosphopyridine Nucleotidase in Uncomplicated Streptococcal Pharyngitis and in Rheumatic Fever *

Serum Inhibition of Streptococcal Diphosphopyridine Nucleotidase in Uncomplicated Streptococcal Pharyngitis and in Rheumatic Fever *

The Analysis of Streptococcal Infections

Acute Encephalomyelitis: Extending the Neurological Manifestations of Acute Rheumatic Fever?

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