A comparative evaluation of health related quality of life and depression in patients with fibromyalgia syndrome and rheumatoid arthritis

Tander, Berna; Cengiz, K.; Alaylı, Gamze; Ilhanli, Ilker; Canbaz, Sevgi; Cantürk, Ferhan

doi:10.1007/s00296-008-0551-6

Cited by 87 publications

(94 citation statements)

References 24 publications

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“…In the RA group, DAS28-4v correlated significantly with all SF-36 subgroups, while in the FM group, DAS28-4v showed weak correlations only with the subgroups regarding general and mental health. The results of the present study are partially in accordance with the results of other studies (1,9,18). Patients with FM report that they have more difficulties in work-related and daily-living activities than RA patients because of severe pain and physical and emotional disability (1).…”

Section: Discussionsupporting

confidence: 83%

“…The results of the present study are partially in accordance with the results of other studies (1,9,18). Patients with FM report that they have more difficulties in work-related and daily-living activities than RA patients because of severe pain and physical and emotional disability (1). However, the loss in physical function resulting from the joint deformities of RA, which is an inflammatory disease, is more than in FM, which is a noninflammatory disease.…”

Section: Discussionsupporting

confidence: 82%

“…Musculoskeletal diseases such as rheumatoid arthritis (RA) and fibromyalgia (FM) are the most important chronic diseases that cause corruption in the quality of life (1). RA is a chronic systematic inflammatory disease, the main symptom of which is peripheral synovitis.…”

Section: Introductionmentioning

confidence: 99%

“…The Short Form-36 (SF-36) is a generic instrument that has been developed to identify the health condition, and it has been used recently in clinical studies as the complementary result-measuring method specific to disease (8). The SF-36 is widely used in patients with RA and FM in order to evaluate the quality of life (1,4,9).…”

Section: Introductionmentioning

confidence: 99%

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Comparative Results of DAS28 and Quality of Life in Patients with Rheumatoid Arthritis and Fibromyalgia

et al. 2010

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Objective: In the present study, we compared Disease Activity Score 28-4v (DAS28-4v) and quality of life by using Short Form-36 (SF-36) in patients with rheumatoid arthritis (RA) and fibromyalgia (FM). Materials and Methods:The swollen joint count (SJC) and the tender joint count (TJC) of 79 patients with RA and 34 patients with FM, the Patient Global Assessment (PGA) with 100 mm visual analog scale (VAS), and erythrocyte sedimentation rates (ESR) were recorded and DAS28-4v scores were calculated. The quality of life in both groups was evaluated by using SF-36. Result: The mean DAS28-4v score of the RA group was 3. 63±1.52 (0.77-7.40) and of the FM group was 2. 42±0.73 (0.57-3.86), and the difference between groups was statistically significant (p<0.001). In the Principal Component Analysis (PCA), in the RA group, the components that most affected DAS28-4v were TJC and SJC, while in the FM group, these were SJC and PGA. Significant differences were detected between the two groups in most SF-36 subgroups, except in the general mental health, social functioning and social role limitation subgroups. In the FM group, the physical function subgroup was significantly higher (p<0.001). Conclusion: Although there is no objective injury such as inflammation or joint damage, FM can decrease the quality of life to the same extent as RA. FM, which is a non-inflammatory disease, can cause high rates in DAS28-4v due to the fact that there are many subjective complaints such as the TJC and the PGA. The intervening infections during the evaluation of disease activity in RA or concomitant diseases like FM might cause fluctuations in the DAS28-4v score. (Turk J Rheumatol 2010; 25: 179-83

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Section: Discussionsupporting

confidence: 83%

Section: Discussionsupporting

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Comparative Results of DAS28 and Quality of Life in Patients with Rheumatoid Arthritis and Fibromyalgia

et al. 2010

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“…Some studies show a positive correlation between depression and RA disease activity scores [59–61] while others do not [32,46]. Regardless of acute disease activity measures, there is no doubt that limited function, as measured by the Health Assessment Questionnaire, is a strong predictor of depression in patients with RA [5,10,11,54,56,59,62,63].…”

Section: Patient and Ra Disease Factors Related To Depressionmentioning

confidence: 99%

Assessment of sleep health in patients with rheumatic disease

Margaretten

Julián²,

Katz³

et al. 2011

International Journal of Clinical Rheumatology

101

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Two sets of contributory factors to depression among patients with rheumatoid arthritis (RA) are generally examined – the social context of the individual and the biologic disease state of that person’s RA. This article will review the evidence for both. RA affects patients both physically and psychologically. Comorbid depression is common with RA and leads to worse health outcomes. Low socioeconomic status, gender, age, race/ethnicity, functional limitation, pain and poor clinical status have all been linked to depression among persons with RA. Systemic inflammation may also be associated with, cause, or contribute to depression in RA. Understanding the socioeconomic factors, individual patient characteristics and biologic causes of depression in RA can lead to a more comprehensive paradigm for targeting interventions to eliminate depression in RA.

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Predictors of depression in a multiethnic cohort of patients with rheumatoid arthritis

Margaretten¹,

Yelin²,

Imboden³

et al. 2009

Arthritis & Rheumatism

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Objective. Patients with rheumatoid arthritis (RA) who experience depression have worse health outcomes. This study identifies predictors of depression in an ethnically and racially diverse population of patients with RA. Methods. Patients with RA in a prospective cohort at the San Francisco General Hospital outpatient rheumatology clinic were included if they were age >18 years, met the American College of Rheumatology classification criteria for RA, had a Health Assessment Questionnaire (HAQ) score collected, and had the RA-specific Disease Activity Score performed by a rheumatologist. The outcome variable was a depression score measured by the Patient Health Questionnaire 9 (PHQ-9), a self-report questionnaire validated to correlate with a diagnosis of major depression. Results. Three hundred forty-nine clinical visits for 172 patients were included in the analysis. Forty percent of patients scored >10 on the PHQ-9 during at least one clinic visit, which corresponds to a symptom severity of at least moderate depression. The mean PHQ-9 score was 7, corresponding to a symptom severity of mild depression. In the multivariate analysis, higher HAQ scores were associated with depression, and Asians had lower depression scores compared with Hispanic, white, and African American subjects. Conclusion. Identifying associated predictors of depression in a diverse population of patients with RA can help guide treatment, which should include preventing disability and decreased function as well as targeting depressive symptoms more specifically in patients with RA.

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A comparative evaluation of health related quality of life and depression in patients with fibromyalgia syndrome and rheumatoid arthritis

Cited by 87 publications

References 24 publications

Comparative Results of DAS28 and Quality of Life in Patients with Rheumatoid Arthritis and Fibromyalgia

Comparative Results of DAS28 and Quality of Life in Patients with Rheumatoid Arthritis and Fibromyalgia

Assessment of sleep health in patients with rheumatic disease

Predictors of depression in a multiethnic cohort of patients with rheumatoid arthritis

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