2016
DOI: 10.1016/j.ajic.2015.11.017
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A comparative evaluation of antimicrobial coated versus nonantimicrobial coated peripherally inserted central catheters on associated outcomes: A randomized controlled trial

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Cited by 24 publications
(11 citation statements)
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“…A recent randomized controlled trial did not demonstrate any difference in the incidence of CLABSI between antimicrobial-coated (chlorhexidine) and nonantimicrobial-coated PICC lines. 15 Interestingly, Brooker and Keenan described the incidence of CLABSI with indwelling catheter to be similar to the incidence associated with line removal. They recommended that there was no evidence to support the use of antibiotic prophylaxis.…”
Section: Discussionmentioning
confidence: 95%
See 1 more Smart Citation
“…A recent randomized controlled trial did not demonstrate any difference in the incidence of CLABSI between antimicrobial-coated (chlorhexidine) and nonantimicrobial-coated PICC lines. 15 Interestingly, Brooker and Keenan described the incidence of CLABSI with indwelling catheter to be similar to the incidence associated with line removal. They recommended that there was no evidence to support the use of antibiotic prophylaxis.…”
Section: Discussionmentioning
confidence: 95%
“…Several other studies have investigated the role of antibiotics in reducing the incidence of CLABSI with indwelling catheters or during line removal. [12][13][14][15] The use of vancomycin-heparin lock solution was found to reduce the overall incidence of CLABSI in the neonates with long-term central line in place, without evidence of emerging antibiotic resistance. 12 Another study demonstrated a decreased incidence of CLABSI with addition of a small dose of vancomycin to continuous TPN.…”
Section: Discussionmentioning
confidence: 99%
“…The impact of chlorhexidine (CHG)-impregnated versus non-CHG PICCs on risk of CLABSI was evaluated in the study by Storey in 2016. After analyzing data from 167 patients, it was shown that no significant difference was noted in the development of CLABSI in the two groups of patients [17].…”
Section: Literature Retrievedmentioning
confidence: 99%
“…A meta-analysis of 7 randomized control trials found that rifampicin-impregnated central venous catheters led to a significant reduction in the CRBSI rate ( OR 0.23, 95% CI : 0.14–0.40) 14 . However, another study of peripherally inserted central catheters that compared chlorhexidine (CHG) impregnated and non-CHG catheters found no difference in CRBSI between the groups 15 . The latest review published in 2016 from Cochrane indicated that the antimicrobial impregnated central venous catheter significantly reduced CRBSI ( RR 0.62, 95% CI : 0.52–0.74) but no effects were observed in minimizing sepsis or mortality 16 …”
Section: Other Modalities To Reduce Infectionmentioning
confidence: 99%