A comparative clinical study of Nyagrodhadi Ghanavati and Virechana Karma in the management of Madhumeha

Abstract

Diabetes mellitus is a common chronic metabolic disorder prevalent all over the world. Virechana is the Shodhana procedure that is specific for the elimination of vitiated Pitta and Kapha doshas. Thus, in the present study, the Virechana process has been selected prior to the administration of Shamana drug. Nyagrodhadi churna is mentioned in Chakradatta, which is modified into Ghana form for easy administration and dose maintenance. The present study was conducted in two groups: Group A, Nyogrodhadi Ghana vati (Shamana therapy) and Group B, Virechana and Nyogrodhadi Ghana vati (combined therapy). A total of 42 patients were registered for the present study, in which 34 patients completed the and eight patients were dropouts. After evaluating the total effect of the therapies, it was observed that the Virechana and Nyagrodhadi Ghanavati (combined therapy) provided better relief in the patients of Madhumeha in comparison with Nyagrodhadi Ghanavati (Shamana therapy) alone.

Effect of Holistic Module of Yoga and Ayurvedic Panchakarma in Type 2 Diabetes Mellitus—A Pilot Study

“…To the best of our knowledge, there are no studies which report the effect of a combination of Yoga and Ayurveda (panchakarma and maintenance therapy) although there are studies on these two therapeutic modalities used independently in comparison to conventional medicine. Kumari et al [8]. Assessed the effect of panchakarma followed by maintenance ayurvedic herbal therapy in forty two subjects with T2DM, which showed significant reduction in FBG and PPBG by 10.2% and 6.4% respectively after one month of intervention.…”

“…This is achieved through satkriyas (Yoga) or panchakarma (Ayurveda). The stepwise progression of panchakarma starts with stimulating the excretion of the endotoxins (ama) through Snehana-Abhyangam (external and internal oleation through medicated massage) and swedana (induced sweating) followed by Virechana that helps in dislodging the vitiated doshas (excess kapha and pitta) [8] through purgation. This is followed by sanshamana (soothing relaxation) through herbal therapies for maintenance of balance.…”

“…Several studies have shown the beneficial effects of Ayurveda in T2DM with significant reduction in Glycosylated Haemoglobin (HbA1c), Fasting and Post Prandial Blood Glucose (FBG, PPBG) levels and lipids [6][7][8]. A study by Ahmed et al that treated diabetic rats with the fruit juice of Momordia charantia has reported regeneration or increase in the number of beta cells [9], which appears to offer some evidence to the additional benefits of Ayurveda because none of the conventional Oral Hypoglycemic Agents (OHA) exhibit this property.…”

“…Although there are many studies that reveal the efficacy of CAM modalities, there are very few studies which report the efficacy of these modalities when used together. Since there are ample evidences that Ayurveda can be a potential complimentary therapy for diabetes [6][7][8], it would be worthwhile to test its efficacy when combined with Yoga, which is also one of the CAM modalities having large number evidence based studies supporting its effect in type 2 diabetes.…”