A Comparative Analysis of Three Methods of Contraception: Effects on Blood Glucose and Serum Lipid Profiles

Mostafavi, H; Abdali, Khadijeh; Zare, Najaf; Rezaian, Gholam Reza; Ziyadlou, Samaneh; Parsanejad, M E

doi:10.5144/0256-4947.1999.8

Cited by 7 publications

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, the LDL-C and TC levels in DMPA users were significantly higher than those in the control subjects. This finding is in agreement with the previous studies [6, 13, 14]. Unlike our study, the studies by Grönroos and Lehtonen [3] and Fajumi [15] showed a decrease in TC levels, whereas those by Faddah et al [6] and Garza-Flores et al [5] did not show any changes in TC levels in DMPA users.…”

supporting

confidence: 93%

Effects of Long-term Use of Depo-medroxyprogesterone Acetate on Lipid Metabolism in Nepalese Women

et al. 2011

View full text Add to dashboard Cite

Various synthetic progestogens that are used as contraceptives have been reported to influence lipid and lipoprotein fractions differently. Depo-medroxyprogesterone acetate (DMPA), a synthetic progestogen, is used by Nepalese women as a contraceptive agent. Our study aims to determine the effects of long-term use of DMPA on lipid metabolism. We performed this study on 60 healthy Nepalese women who had been using DMPA for more than 2 yr and age- and weight-matched control subjects who were not using hormonal contraceptives. Fasting blood samples were collected from the subjects for the estimation of total cholesterol (TC) and triglyceride (TG) levels, and the levels of high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were estimated using the Friedewald's equation. TC and LDL-C levels in DMPA users were significantly higher than those in non-users. Our study concluded that DMPA use induces lipid metabolism changes that can increase the risk of cardiovascular diseases.

show abstract