2021
DOI: 10.2174/1874944502114010128
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A Comparative Analysis of the Spanish Flu 1918 and COVID-19 Pandemics

Abstract: Two devastating pandemics, the Spanish Flu and COVID-19, emerged globally in 1918 from America and 2019 from China, respectively. Influenza virus A H1N1, which caused Spanish Flu and SARS-CoV2, which caused COVID-19, belong to different virus family and bear different structure, genomic organization and pathogenicity. However, the trajectory of the current outbreak of COVID-19 depicts a similar picture of the Spanish Flu outbreak. Estimates suggest that ~500 million infected cases and ~50 million deaths occurr… Show more

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Cited by 16 publications
(19 citation statements)
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“…For this reason, COVID-19 pandemic become the largest and the most diverse pandemic since the 1918 influenza pandemic, as the number of cases that are increasing on a daily base across 200 countries. The unprecedented spread of this pandemic disease is mainly due to its transformation through short distance human to human contact [ 2 ].…”
Section: Introductionmentioning
confidence: 99%
“…For this reason, COVID-19 pandemic become the largest and the most diverse pandemic since the 1918 influenza pandemic, as the number of cases that are increasing on a daily base across 200 countries. The unprecedented spread of this pandemic disease is mainly due to its transformation through short distance human to human contact [ 2 ].…”
Section: Introductionmentioning
confidence: 99%
“…The “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)” is a highly contagious, challenging, and threatening illness that swiftly spreads worldwide ( 1 ). The World health organization (WHO) declared COVID-19 a global pandemic and considered it the fifth pandemic globally since the Spanish flu pandemic in 1918 ( 2 ). The SARS-CoV-2 virus is transmitted through direct contact with an infected person ( 3 ).…”
Section: Introductionmentioning
confidence: 99%
“…The COVID-19 pandemic has often been compared to the Spanish flu. For example, He et al (2020) discussed the epidemiological similarities between the two pandemics in the UK, whereas Agrawal et al (2021) noted similar trajectories at the beginning of each outbreak. It has been estimated that the Spanish flu killed 50-100 million people around the world (2.3 million in Europe) between 1918 and 1920 (Johnson and Mueller, 2002), and thus up to 5% of the global population at that time (0.5% of the population in Europe).…”
Section: Discussionmentioning
confidence: 99%