A compact representation of the bone fracture area. Application to fractured bones of clinical cases

Luque-Luque, Adrián; Jiménez-Pérez, J. Roberto; Cano, F.; Jiménez-Delgado, Juan José

doi:10.1080/21681163.2020.1850365

Cited by 2 publications

(3 citation statements)

References 7 publications

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“…Finally, the candidate points are filtered based on their distance to the candidate points of the opposite fragment. Luque-Luque et al [44] proposed an improvement to this method by using an oriented plane to obtain a refined fracture zone. They also used filters based on curvature and statistical parameters to remove outliers.…”

Section: Fracture Zone Analysismentioning

confidence: 99%

“…A fracture pattern can be obtained from the fracture zone defined by a point cloud. This is the most-used representation of bone fracture patterns since most of the work in this area focuses on the fracture-reduction process, which involves 3D representations of the bone fractures [35][36][37][43][44][45][46]. There are several methods to represent the fracture pattern obtained such as the point cloud itself, height maps, or triangle meshes.…”

Section: Point Cloudsmentioning

confidence: 99%

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Exploring Fracture Patterns: Assessing Representation Methods for Bone Fracture Simulation

Pérez-Cano,

Parra-Cabrera,

Vilchis-Torres

et al. 2024

JPM

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Fracture pattern acquisition and representation in human bones play a crucial role in medical simulation, diagnostics, and treatment planning. This article presents a comprehensive review of methodologies employed in acquiring and representing bone fracture patterns. Several techniques, including segmentation algorithms, curvature analysis, and deep learning-based approaches, are reviewed to determine their effectiveness in accurately identifying fracture zones. Additionally, diverse methods for representing fracture patterns are evaluated. The challenges inherent in detecting accurate fracture zones from medical images, the complexities arising from multifragmentary fractures, and the need to automate fracture reduction processes are elucidated. A detailed analysis of the suitability of each representation method for specific medical applications, such as simulation systems, surgical interventions, and educational purposes, is provided. The study explores insights from a broad spectrum of research articles, encompassing diverse methodologies and perspectives. This review elucidates potential directions for future research and contributes to advancements in comprehending the acquisition and representation of fracture patterns in human bone.

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Section: Fracture Zone Analysismentioning

confidence: 99%

Section: Point Cloudsmentioning

confidence: 99%

Exploring Fracture Patterns: Assessing Representation Methods for Bone Fracture Simulation

Pérez-Cano,

Parra-Cabrera,

Vilchis-Torres

et al. 2024

JPM

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show abstract

“…[1][2][3] In their natural niche microenvironments, the lineage commitment of hMSC is regulated by different signals, including mechanical stimuli, soluble factors, and cell-extracellular matrix (ECM) interactions. [4][5][6] While delayed reunion of fractured bone remains a major clinical complication of surgery despite advances in operation techniques, [7] direct injection of hMSC into bone defects generally leads to limited stem cell grafting and differentiation due to the lack of necessary biochemical cues in the cell-delivery systems. [8,9] Developing osteoinductive biomaterial scaffolds by incorporating Stem cell bioengineering and therapy require different model systems and materials in different stages of development.…”

Section: Introductionmentioning

confidence: 99%

A Self‐Assembled Matrix System for Cell‐Bioengineering Applications in Different Dimensions, Scales, and Geometries

Gaillez

Zheng

et al. 2022

Small

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Stem cell bioengineering and therapy require different model systems and materials in different stages of development. If a chemically defined biomatrix system can fulfill most tasks, it can minimize the discrepancy among various setups. By screening biomaterials synthesized through a coacervation‐mediated self‐assembling mechanism, a biomatrix system optimal for 2D human mesenchymal stromal cell (hMSC) culture and osteogenesis is identified. Its utility for hMSC bioengineering is further demonstrated in coating porous bioactive glass scaffolds and nanoparticle synthesis for esiRNA delivery to knock down the SOX‐9 gene with high delivery efficiency. The self‐assembled injectable system is further utilized for 3D cell culture, segregated co‐culture of hMSC with human umbilical vein endothelial cells (HUVEC) as an angiogenesis model, and 3D bioprinting. Most interestingly, the coating of bioactive glass with the self‐assembled biomatrix not only supports the proliferation and osteogenesis of hMSC in the 3D scaffold but also induces the amorphous bioactive glass (BG) scaffold surface to form new apatite crystals resembling bone‐shaped plate structures. Thus, the self‐assembled biomatrix system can be utilized in various dimensions, scales, and geometries for many different bioengineering applications.

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A compact representation of the bone fracture area. Application to fractured bones of clinical cases

Cited by 2 publications

References 7 publications

Exploring Fracture Patterns: Assessing Representation Methods for Bone Fracture Simulation

Exploring Fracture Patterns: Assessing Representation Methods for Bone Fracture Simulation

A Self‐Assembled Matrix System for Cell‐Bioengineering Applications in Different Dimensions, Scales, and Geometries

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