A compact linac for intensity modulated proton therapy based on a dielectric wall accelerator

Caporaso, G.J.; Mackie, Thomas Rockwell; Sampayan, S.; Chen, Y. J.; Blackfield, D.; Harris, John R.; Hawkins, Steven A.; Holmes, C.; Nelson, Scott D.; Paul, A.C.; Poole, B.; Rhodes, M.; Sanders, D.; Sullivan, J.; Wang, L.; Watson, J.; Reckwerdt, Paul; Schmidt, R.; Pearson, D; Flynn, Robert; Matthews, Dennis L; Purdy, James A.

doi:10.1016/j.ejmp.2008.01.010

Cited by 45 publications

(22 citation statements)

References 4 publications

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“…13, has been reported by Caporaso et al (2008 (Caporaso et al 2008)] The goal is to make a PBRT linac so compact that it can be installed in a conventional linac treatment room. This will require an average accelerating gradient of approximately 100 MV/m to yield a linac of the order of 2 m in length.…”

Section: 6mentioning

confidence: 97%

Physics of Radiotherapy Planning and Delivery

et al. 2011

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Section: 6mentioning

confidence: 97%

Physics of Radiotherapy Planning and Delivery

et al. 2011

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“…10 ns. Development of suitable so-called high-gradient insulators may sustain electric fields up to as much as 100 MV m −1 ; a laser-driven Blumlein switch causes this pulse to travel along a stack of dielectric rings in step with the accelerated particles [102][103][104]. If achieved in a complete accelerator, such a gradient would allow a complete acceleration system to 250 MeV to be only several metres in length.…”

Section: Dielectric Wall Acceleratorsmentioning

confidence: 99%

Hadron accelerators for radiotherapy

Owen

Mackay

Peach

et al. 2014

Contemporary Physics

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Over the last twenty years the treatment of cancer with protons and light nuclei such as carbon ions has moved from being the preserve of research laboratories into widespread clinical use. A number of choices now exist for the creation and delivery of these particles, key amongst these being the adoption of pencil beam scanning using a rotating gantry; attention is now being given to what technologies will enable cheaper and more effective treatment in the future. In this article the physics and engineering used in these hadron therapy facilities is presented, and the research areas likely to lead to substantive improvements. The wider use of superconducting magnets is an emerging trend, whilst further ahead novel high-gradient acceleration techniques may enable much smaller treatment systems. Imaging techniques to improve the accuracy of treatment plans must also be developed hand-in-hand with future sources of particles, a notable example of which is proton computed tomography.

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“…It uses a fast switched high-voltage transmission line to generate pulsed electric fields inside the acceleration tube. An accelerating electric field gradient is achieved by use of alternating insulators and conductors [11]. A programme to develop DWA for clinical application is currently underway, but clinically relevant energies are yet to be achieved.…”

Section: Dielectric Wall Acceleratormentioning

confidence: 99%