A common presentation of uncommon disease – Biliary Fasciola Hepatica

Abstract

Hepatobiliary fascioliasis is one of the rare but important parasitic infection in endemic areas such as Pakistan. Clinical manifestations overlap with common clinical conditions such as hepatitis and biliary stones causing common bile duct obstruction. Fascioliasis is a zoonotic infection caused by a leaf-shaped organism known as Fasciola Hepatica. Humans are accidentally infected by consuming contaminated water or food, especially undercooked cattle and sheep liver or raw green vegetables. We report three cases with similar clinical manifestations presenting in two different cities in Pakistan. After detailed clinical evaluation and laboratory investigations, the diagnosis was established by abdominal ultrasound and diagnostic and therapeutic cholangiography. Patients were followed till complete resolution of their symptoms and normalisation of liver function tests.

Distinctive Histopathological Features of Fasciola Hepatica Adult

“…6 Additionally, live parasites can be detected through methods such as ERCP not only in patients initially suspected of having fascioliasis but also in those without initial suspicion due to vague symptoms and findings. 7,8 Radiological findings may be nonspecific and include filling defect, biliary sludge, and enlargement of the biliary tract. 9 Obstruction of the bile ducts could be caused both by the parasite itself and its products.…”