A common cause of hair loss?

King, Natalie; Mesiano, D.; Ahmed, Iqbal; Carr, Richard

doi:10.1111/ced.14452

Cited by 1 publication

(1 citation statement)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Small molecule PDE4 inhibitors like apremilast, which increase the concentration of intracellular cyclic AMP, are an example for drugs that can be effective in the management of scalp psoriasis, [101][102][103] but are also HFprotective in that they can inhibit the development of experimentally Note: Even though the pilosebaceous unit is clearly affected by scalp psoriasis on multiple levels and the percentage of catagen/telogen HFs can be increased, as summarized in the table, even with severe scalp involvement, psoriatic alopecia occurs only in a small minority of patients. 28,184,185 Moreover, only in a minority of patients there is loss of visible hairs within psoriatic plaques. 29…”

Section: Pde4 Inhibitorsmentioning

confidence: 99%

The hair follicle‐psoriasis axis: Shared regulatory mechanisms and therapeutic targets

Suzuki

Ito

Gilhar

et al. 2021

Experimental Dermatology

View full text Add to dashboard Cite

Physicians and investigators interested in either psoriasis or hair growth rarely interact to discuss pathways and mechanisms of potential common interest. And yet, it has long been recognized that both fields intersect closely and show more overlap than is widely appreciated. [1][2][3][4][5][6][7][8][9] Here, we review the relevant literature that points to a special relationship between the hair follicle (HF) and psoriasis and explain why a systematic re-examination of this axis is clinically relevant and promises to enrich both psoriasis and hair research.After we had first postulated that the induction of a psoriatic epidermal lesion and of anagen hair growth share selected "switch-on" mechanisms, 2 this concept was re-voiced in part two decades later 7 yet remains largely ignored and has not been rigorously probed until

show abstract