“… 8 , 19 , 20 , 23 , 29-35 Ten studies reported gender of which 95.7% was female (n = 870). 8 , 19 , 20 , 23 , 29 , 31-35 Of the studies enrolled in this systematic review, 6 assessed an invasive technique to lift oral commissures in 426 patients 19 , 20 , 23 , 30-32 ( Supplemental Table 1 ) and 5 studies assessed a noninvasive technique in 536 patients 8 , 29 , 33-35 ( Supplemental Table 2 ). All studies reported the mean age or age variance of the patients and 7 studies 8 , 20 , 23 , 29 , 33-35 described differences in ethnicity or skin type on the Fitzpatrick scale ( Supplemental Tables 1 and 2 ).…”