A clinicopathological study on laryngeal cancer (Preprint)

Abstract

BACKGROUND The study was conducted at Governemnt Rajaji Hospital OBJECTIVE Laryngeal cancer is primarily a disease of middle aged men. It has peak incidence in the seventh decade. Worldwide it is the common head and neck cancer. Squamous cell carcinoma is the most common type of tumor, comprising 90 percent or more of all laryngeal malignancies. Laryngeal cancer is more common in areas with higher levels of social poverty. The study is done to find out the common clinical presentation of patients with laryngeal carcinoma with reference to the age profile, the symptomatology, disease stage, etiological factors, occupational history, histological profile and to determine the treatment modalities offered to the laryngeal cancer patients attending ENT OPD at GRH., Madurai. METHODS This is a hospital based prospective study. The study was conducted at Government Rajaji Hospital.,Madurai.,India.All the newly diagnosed laryngeal cancer patients were included in the study between July 2013 to June 2014.Totaly we had 113 patients in this study. RESULTS In our study most of them were male patients. The most common age group Was 65 years.We had only 4 female patients in our study and all had supraglottic growth. All the patients belonged to low socioeconomic strata.The most common part of larynx involved is supraglottis. None of our patients had distant metastasis. The most common presentation was difficulty in breathing and stridor, later followed by change of voice and dysphagia.The common histopathological finding was squmous cell carcinoma. In that moderatelty differentiated was the most common type.The most common stage was stage III. The most common treatment offered at our hospital was concurrent chemoradiotherapy. CONCLUSIONS Diagnosis of laryngeal cancer is based on good history, clinical examination, direct examination of the larynx, CT scan and supported by histopathological examination. This study has been done to increase awareness on early diagnosis and treatment which leads to the better life style of the laryngeal cancer patients.