A clinicoepidemiological study of polymorphic light eruption

Sharma, Lata; Basnet, Aparna

doi:10.4103/0378-6323.38400

Cited by 16 publications

(29 citation statements)

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“…In a study done by Sharma et al in Varanasi, the prevalence was 0.56% and in another study by Prasad et al the prevalence was 0.49%. 6,8 PMLE is considered to be a disease of fair skinned individuals. 2 So the western population showed a higher prevalence.…”

Section: Discussionmentioning

confidence: 99%

“…9,10 In Sharma et al study 62.73% were females and in Prasad et al study 63% were females. 6,8 Women were more frequently affected than men. Female preponderance could be attributed to the recent demonstration of a female hormone 17-β estradiol which prevents UVR induced suppression of the contact hypersensitivity response caused by the release of immunosuppressive cytokines (IL-10) from keratinocytes.…”

Section: Gender Distributionmentioning

confidence: 99%

“…6 Several authors have speculated that PMLE is inherited as an autosomal dominant gene with reduced penetrance but recent studies have shown a polygenic inheritance. [19][20][21] The heritability of PMLE varied between 6.25% -12% in the studies conducted by Ross and Millard.…”

Section: Family Historymentioning

confidence: 99%

“…Farmers (10%) were less commonly affected in their study. 6 In Prasad et al study, 60% were manual laborers and 19% were students. …”

Section: Occupation Of the Study Populationmentioning

confidence: 99%

“…[2][3][4][5] The prevalence of PMLE in India is 0.56%. 6 This is probably due to the development of UVR induced immunologic tolerance, sometimes referred to as "hardening", secondary to constant solar exposure in sunny climate.…”

Section: Introductionmentioning

confidence: 99%

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A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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Introduction: Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. The prevalence of PMLE varies from 5% to 15% in various studies across the world and in India it is 0.56%.Objective: The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption.Material and Method: A cross sectional prospective study was conducted in Dermatology OPD between April 2015 and June 2016. A total of 100 patients with symptoms and signs of PMLE were included in the study. Data were coded and analyzed.Results: Majority of the cases in our study were in the age group of 21 - 30 years (36%). It was more common in females (82%) when compared with males (18%). Occupation of most of the patients (29%) was farmers in our study population. Positive family history of PMLE was seen in 11% of the study population. The commonest form was the papular type (46%) and the second most common type was plaque type (17%). Regarding the distribution of lesions, about 51% of our study subjects had polymorphic lesions confined to only one area of their body mostly forearm (25%) followed by face (12%).Conclusion: The prevalence of PMLE was 1.34% in our study population. Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.

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Section: Discussionmentioning

confidence: 99%

Section: Gender Distributionmentioning

confidence: 99%

Section: Family Historymentioning

confidence: 99%

“…Farmers (10%) were less commonly affected in their study. 6 In Prasad et al study, 60% were manual laborers and 19% were students. …”

Section: Occupation Of the Study Populationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

et al. 2017

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Photosensitivity and Photoreactions in Pediatric Skin of Color

Feely

Leo

2015

Pediatric Skin of Color

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Photodermatoses in the Pigmented Skin

Sharma

Sahni

2017

Advances in Experimental Medicine and Biology

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Skin colour (specifically in relation to its melanin content and composition) has a marked influence on its interaction with ultraviolet light. Eumelanin has mainly photoprotective properties while pheomelanin has the ability to cause formation of reactive oxygen species. This difference is responsible for the difference in incidence and presentation of various idiopathic photodermatoses in dark skinned patients compared to those with lighter skin types. Certain conditions are peculiar to darker skins including pin point popular variant of polymorphous light eruption. These differences are discussed in this chapter while also highlighting the challenges faced in performing phototesting in patients with dark skin.

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A clinicoepidemiological study of polymorphic light eruption

Abstract: The prevalence of PLE was 0.56%. It was mild in nature and only areas exposed to the sun were involved.

Cited by 16 publications

References 0 publications

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

Photosensitivity and Photoreactions in Pediatric Skin of Color

Photodermatoses in the Pigmented Skin

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