A clinico-histopathological study of lupus vulgaris: A 3 year experience at a tertiary care centre

Abstract

Background:Lupus vulgaris is the most common form of cutaneous tuberculosis in adults. Lupus vulgaris is caused by hematogenous, lymphatic, or contiguous spread from elsewhere in the body. histologically it is charecterised by typical tubercles with or without caseation, surrounded by epitheloid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes.Materials and Method:All cases of clinically and histopathologicaly diagnosed lupus vulgaris over the previous five years were included in the study.Results:Fourteen cases of lupus vulgaris cases reported during the study period with eaqual incidence among males and females.Discussion:Plaque type of lupus vulgaris was the most common type. Histopathologically tubercular granulomas were seen in all cases as compared to other studies.Conclusion:Different patterns of lupus vulgaris are reported

Chronic oozing skin lesions in children: Possible tuberculosis? Two case reports

“…Absence of caseation was reported in LV. Pai et al [16] reported fourteen cases of LV in which histopathological examination revealed lymphocytic infiltrates, Langerhans cells, and epithelioid granulomas, with caseation in three out of 14 cases (27.2%) and granulomas without caseation in 11 out of 14 cases (78.5%) [16]. Endogenous infection resulting from hematogenous spread of the infection or direct extension is the possible route of infection [17].…”

SkIndia quiz 36: A phantasmagoric lesion: A face for thought

“…It is the most common form of cutaneous TB in adults in the Indian subcontinent and South Africa. [1] All age groups are equally affected, with females two to three times more commonly than males. [1] The most prominent histopathologic feature is the formation of typical tubercles with or without caseation, surrounded by epithelioid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes.…”

“…[1] All age groups are equally affected, with females two to three times more commonly than males. [1] The most prominent histopathologic feature is the formation of typical tubercles with or without caseation, surrounded by epithelioid histiocytes and multinucleate giant cells in the superficial epidermis with prominent peripheral lymphocytes. Secondary changes such as epidermal thinning and atrophy or acanthosis with excessive hyperkeratosis or pseudoepitheliomatous hyperplasia can also be noted.…”

“…A clinical response would be expected within 4–6 weeks. [1] Our patient was referred to the DOTS center where she was started on the Category 1 regime.…”

Bleeding erythematous papules over nose in a middle‐aged man

“…The most commonly affected sites include the trunk, buttocks, and extremities . It can present in a variety of morphological forms, including papular, nodular, plaque, ulcerative, vegetative, and tumor‐like lesions . Untreated lupus vulgaris may lead to various complications such as ulceration, scarring, and destruction of the nasal vestibule, tip, and alae nasi, thus early diagnosis and management is essential.…”