A Clinical Variant of Chancroid Resembling Granuloma Inguinale

Hemophilus ducreyi infection resembling granuloma inguinale

“…Giemsa's stain applied to smears of ulcer exudate is often unreliable as diagnostic proof due to contamination with other similar genital bacteria (6, 7). The clinical appearance of the lesions in our patient was similar to those previously reported in patients with granuloma inguinale-like Hemophilus ducreyi infection (5,6). It has not yet been established why Hemophilus ducreyi in some cases produces lesions similar to infections due to Calymmatobacterium (Donovania) granuloma tis.…”

“…It has not yet been established why Hemophilus ducreyi in some cases produces lesions similar to infections due to Calymmatobacterium (Donovania) granuloma tis. Altered immune response to Hemophi/11s ducreyi has been suggested (6), but in our patient the history did not indicate an abnorma! course of other types of infections.…”

“…8). Tetracycline or sulphonamides have been recommended for treatment of chancroid ( 9), but cases of relative resistance of Hemophilus ducreyi to one or both drugs has been reported (6,8). Tetracycline was given initially to our patient, because granuloma inguinale was suspected (9).…”

“…The base is covered by a purulent exudate, and a painful inguinal lymphadenitis (bubo) is common (I, 2, 4), Table I. The diagnosis of chancroid must be confirmed by demonstration of Hemophilus ducreyi from the lesions because clinical confusion with granuloma inguinale may occur (5,6). A case of Hemophi/us ducreyi infection clinically resembling granuloma inguinale is reported herein.…”