A Clinical Trial of Fiberoptic Phototherapy vs Conventional Phototherapy

Holtrop, Paul C.; Madison, Kathi C.; Maisels, M. Jeffrey

doi:10.1001/archpedi.1992.02160140101029

Cited by 15 publications

(20 citation statements)

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“…Because of the different spectra of the two types of light, the irradiance values of the Biliblanket were 867 W/cm 2 2 , respectively. In the double-fiber-optic setup the total irradiance would be twice that of the standard fiber-optic mat.…”

Section: Methodsmentioning

confidence: 99%

“…[1][2][3] The fiber-optic Biliblanket device (Ohmeda Critical Care, Columbia, MD) was found to be more effective than the Wallaby phototherapy system (Fiberoptic Medical Products Inc, Allentown, PA). 4 However, in our experience the efficacy of the standard-size mat for full-term infants is distinctly less than that of conventional phototherapy using our own setup 5 ; this was attributed to the relatively small size of the mat, resulting in exposure of the skin being limited to a small area.…”

mentioning

confidence: 99%

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Efficacy of Bidirectional Fiber-optic Phototherapy for Neonatal Hyperbilirubinemia

Tan

1997

Pediatrics

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ABSTRACT. Objective. To evaluate the efficacy of fiber-optic phototherapy using the standard Ohmeda Biliblanket, a large version, double standard Biliblankets, and conventional phototherapy using daylight fluorescent lamps in full-term, healthy infants with nonhemolytic hyperbilirubinemia.Methods. Full-term, healthy infants with nonhemolytic hyperbilirubinemia (bilirubin concentration, >255 mol/L or 222 mol/L at <48 hours of age) were allocated randomly to one of four modes of phototherapy: standard fiber-optic mat (Ohmeda Biliblanket), a large version, double standard Biliblankets, and conventional phototherapy. Bilirubin levels were monitored every 12 hours. Exposure was stopped when bilirubin levels were less than 185 mol/L, the minimum duration being 24 hours.Results. A total of 171 infants were studied; 42 were exposed to standard fiber-optic phototherapy, 43 to large fiber-optic phototherapy, 42 to double-fiber-optic phototherapy, and 44 to conventional phototherapy. Durations of exposure were 87.05 ؎ 6.09 (SEM), 82.57 ؎ 5.84, 64.85 ؎ 5.43, and 62.61 ؎ 3.74 hours, respectively; the 24-hour decline rates were 10.26% ؎ 1.84%, 14.50% ؎ 1.53%, 21.82% ؎ 1.71%, and 19.00% ؎ 1.65%, respectively; the overall decline rates over the whole exposure period were 0.47% ؎ 0.03%, 0.52% ؎ 0.04%, 0.71% ؎ 0.05%, and 0.75% ؎ 0.04% per hour, respectively. The efficacy of double-fiber-optic phototherapy and conventional phototherapy was similar and significantly better than that of the large fiber-optic mat and the standard fiber-optic mat in duration, 24-hour decline rate, and overall decline rate. The large mat was slightly better than the standardsize mat with regard to 24-hour decline rate and overall decline rate, but this difference was not significant. Failure of phototherapy occurred only in the large fiber-optic mat group (3 of 43) and the standard fiber-optic mat group (4 of 42); none occurred in the other two groups, but differences not statistically significant. The nursing personnel were more comfortable with single fiber-optic phototherapy, which caused no initial disturbance to the swaddled infants as did conventional phototherapy, but found double-fiber-optic phototherapy difficult to use.Conclusion. For efficacy of fiber-optic phototherapy in full-term infants to be comparable to that of our conventional phototherapy, the light dose of the standard mats needs to be doubled. Pediatrics 1997;99(5). URL: http://www.pediatrics.org/cgi/content/full/99/5/e13; fiberoptic phototherapy, neonatal hyperbilirubinemia, efficacy.Fiber-optic phototherapy delivered via a fiber-optic cable to a transparent flat device (mat) that can be placed directly in contact with the infant skin has been demonstrated to be effective for neonatal hyperbilirubinemia.1-3 The fiber-optic Biliblanket device (Ohmeda Critical Care, Columbia, MD) was found to be more effective than the Wallaby phototherapy system (Fiberoptic Medical Products Inc, Allentown, PA). 4 However, in our experience the efficacy of the standard-size mat for full-term infant...

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Efficacy of Bidirectional Fiber-optic Phototherapy for Neonatal Hyperbilirubinemia

Tan

1997

Pediatrics

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“…Currently, the biliblanket is used mainly as an adjuvant in double phototherapy, i.e., the newborn lies on the biliblanket while receiving conventional phototherapy. 15,[39][40][41] High intensity phototherapy In the 1990s, new phototherapy devices began to appear. These emitted high radiance distributed along a large body surface.…”

Section: Biliblanket Phototherapymentioning

confidence: 99%

Treatment of neonatal hyperbilirubinemia

Carvalho¹

2001

J Pediatr (Rio J)

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Objective: to review the recent medical literature on the treatment of neonatal jaundice, focusing on practical aspects that are relevant to pediatricians and neonatologists.Sources: an extensive review of the related literature was performed, also including the author's clinical experience in this field of investigation. Summary of the findings:jaundice is very common among infants during the first days of life. Several factors such as maternal and neonatal history have to be considered before implementing treatment. Significant advances have been made in the past few years concerning the treatment of jaundiced newborn infants. This review focuses on three forms of treatment of neonatal hyperbilirubinemia: phototherapy, exchange transfusion and the use of drugs to reduce serum bilirubin concentration.Conclusions: nowadays, the in-depth knowledge about the mechanism of action of phototherapy, the development of intensified phototherapy units and the use of drugs to reduce bilirubin formation, have contributed to significantly decrease the need for exchange transfusion.

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“…7 Similarly, a few studies have addressed the effectiveness of high intensity in lowering the bilirubin concentration. 8,9 To the best of our knowledge, there is only one published study which compared the efficacy of the three forms of phototherapy (fiberoptic, conventional and the combination) in decreasing bilirubin in neonates.…”

mentioning

confidence: 99%

Fiberoptic, Conventional and Combination Phototherapy for Treatment of Nonhemolytic Hyperbilirubinemia in Neonates

Al‐Alaiyan

1996

Ann Saudi Med

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The objective of this prospective, randomized study was to compare the effectiveness of fiberoptic, conventional and a combination phototherapy in decreasing bilirubin concentrations in neonatal nonhemolytic hyperbilirubinemia. Forty-six infants who were 36 weeks' gestation and more were randomly assigned to fiberoptic phototherapy (n=16) (Biliblanket, Ohmeda), conventional daylight phototherapy (n=15) and combination phototherapy (n=15) (fiberoptic and conventional). The groups were similar in clinical characteristics at study entry in terms of birth weight, age and bilirubin concentration. There were no statistically significant differences in the duration of treatment among the three groups (P=0.83). There were also no statistically significant differences among the three groups in the serum bilirubin concentrations at 24 hours, 48 hours, end of phototherapy, and 24 hours postphototherapy. We conclude that the decrease in serum bilirubin concentration was comparable among fiberoptic, conventional and combination phototherapy groups.

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A Clinical Trial of Fiberoptic Phototherapy vs Conventional Phototherapy

Cited by 15 publications

References 4 publications

Efficacy of Bidirectional Fiber-optic Phototherapy for Neonatal Hyperbilirubinemia

Efficacy of Bidirectional Fiber-optic Phototherapy for Neonatal Hyperbilirubinemia

Treatment of neonatal hyperbilirubinemia

Fiberoptic, Conventional and Combination Phototherapy for Treatment of Nonhemolytic Hyperbilirubinemia in Neonates

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