A Clinical Study to Evaluate the Role of Vitamin D3 in Allergic Rhinitis

Kalsotra, Gopika; Saraf, Aditiya; Raina, Apurva; Kalsotra, Parmod; Sharma, Rupali; Hussain, Abid

doi:10.1007/s12070-021-03004-x

Cited by 1 publication

(1 citation statement)

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“…Kalsotra et al evaluated the symptoms in two groups of patients with AR before and 4 weeks after administering oral vitamin D in combination with intranasal steroid sprays to one group and vitamin D alone to another group. After treatment, total nasal symptoms scores (TNSS) were significantly lower in both groups compared with pre-treatment scores, indicating an improvement in rhinitis symptoms and thus a progression towards control of AR (32). In another similar investigation, Modh et al (33) evaluated two groups of 21 patients with AR and compared TNSS before and after routine antiallergic treatment and daily vitamin D supplementation for 21 days in one group and routine treatment only in the other.…”

Section: Discussionmentioning

confidence: 99%

Determinants of uncontrolled allergic rhinitis in Kinshasa hospitals

Kakobo

Kalala²,

Kelekele³

et al. 2023

Front. Allergy

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ObjectiveTo identify the determinants of uncontrolled allergic rhinitis (UCAR) in a hospital setting in Kinshasa, Democratic Republic of Congo.MethodsHospital-based cross-sectional study of 153 patients with allergic rhinitis (AR). The diagnosis of AR was based on clinical grounds according to the Allergic Rhinitis and its Impact on Asthma (ARIA) criteria. Categorization into controlled AR (CAR) and UCAR was based on the visual analog scale (VAS with cut off point of 5). Binary logistic regression was used to identify factors associated with UCAR.ResultsPatients with UCAR (60.1%) proportionally outnumbered those with CAR (39.9%). There were significantly more patients younger than 30 years of age among patients with UCAR. Factors significantly associated with UCAR were age below 30 years (OR = 3.31; 95% CI: 1.49–7.36; p = 0.003), low serum vitamin D level (OR = 3.86; 95% CI: 1.72–8.68; p = 0.001), persistent form (OR = 3.11; 95% CI: 1.39–6.98; p = 0.006) and moderate to severe form of AR (OR = 4.31; 95% CI: 1.77–10.49; p = 0.001).ConclusionsFactors associated with UCAR in this study population were younger age less than 30 years, low vitamin D level, and persistent as well as moderate to severe AR. Further studies are needed to elucidate the underlying mechanisms favoring the occurrence of these factors.

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Section: Discussionmentioning

confidence: 99%