A Clinical Study of
            <sup>99m</sup>
            Technetium Dimercaptosuccinic Acid Uptake in Obstructed Kidneys: Comparison with the Creatinine Clearance

Maeyer, Philippe De; Simons, M.; Oosterlinck, W; Sy, W. A. De

doi:10.1016/s0022-5347(17)52728-7

Cited by 20 publications

(6 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Contrary to what has been observed previously [6] , we found that the correlation between the estimated DRF ok values using CCr and DMSA were highest when the estimated DRF ok was either low (towards 0%) or high (towards 100%) and was lowest at middle values ( 6 20 and ^ 80%) ( fig. 2 ).…”

Section: Commentscontrasting

confidence: 99%

“…However, it has disadvantages such as radiation to the kidney, time delay between injection and imaging, which is normally 2-4 h and which may require a delay of 24 h to obtain an optimal DRF measurement [5] , and the high cost. On the other hand, in patients who undergo insertion of a PCNT for the relief of renal obstruction, CCr has been used to estimate DRF [6] . The drawbacks of this technique are that it requires 24-hour urine collection (which will delay the final results) as well as the need for a serum sample.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Al-Hunayan¹,

Al-Ateeqi²,

Kehinde³

et al. 2008

Urol Int

View full text Add to dashboard Cite

Objectives: To determine the diagnostic accuracy of spot urine creatinine concentration (UCC) as a new test for the evaluation of differential renal function in obstructed kidneys (DRF_ok) drained by percutaneous nephrostomy tube (PCNT). Methods: In patients with obstructed kidneys drained by PCNT, DRF_ok was derived from UCC by comparing the value of UCC in the obstructed kidney to the value in the contralateral kidney, and was derived from dimercaptosuccinic acid (DMSA) renal scans and creatinine clearance (CCr) using standard methods. Subsequently, the results of UCC were compared to the results of DMSA and CCr. Results: 61 patients were enrolled. Bland-Altman plots to compare DMSA and UCC showed that the upper limit of agreement was 14.8% (95% CI 10.7–18.5) and the lower limit was –19.9% (95% CI –23.8 to –16.1). The sensitivity and specificity of detecting DMSA DRF_ok ≤35% using UCC was 85.2 and 91.2%, respectively. When UCC was compared to CCr, Bland-Altman tests gave an upper limit of agreement of 10.4% (95% CI 7.9–12.8) and a lower limit of agreement of –11.3% (95% CI –13.8 to –8.9). Conclusions: UCC is accurate in the estimation of DRF_ok drained by PCNT.

show abstract

Section: Commentscontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Al-Hunayan¹,

Al-Ateeqi²,

Kehinde³

et al. 2008

Urol Int

View full text Add to dashboard Cite

show abstract

“…However, De MAEYER et coil. (5) found in 17 hydronephrotic kidneys owing to stenosis of the pyeloureteral junction an excellent correlation between preoperative uptake of DMSA and early postoperative clearance. In 11 of our 17 patients the hippuran uptake rate after relief of the obstruction was within ±3 per cent units of the DMSA uptake rate before the intervention making the DMSA uptake an acceptable predictor of recovery.…”

Section: Discussionmentioning

confidence: 84%

Combination of DMSA-Scintigraphy and Hippuran Renography in Unilateral Obstructive Nephropathy

et al. 1987

View full text Add to dashboard Cite

The renal handling of dimercaptosuccinic acid and hippuran ?iffers. This might be used in unilateral obstructive nephropathy In order to predict potential functional recovery following intervention. The theory was evaluated on a retrospective basis in 17 patients, who primarily had a nephrostomy. If the DMSA-uptake rate in the diseased kidney was more than 10 per cent higher than that of hippuran, the uptake rate of hippuran increased following relief of obstruction. Use of the two radiopharmaceuticals, thus, may have great impact on the clinical decision, since in case of a difference some function may be saved by immediate intervention.

show abstract

“…The use of delayed studies (24 h) has been suggested (Verboven et al 1987;De Maeyer et al 1982). The use of delayed studies (24 h) has been suggested (Verboven et al 1987;De Maeyer et al 1982).…”

Section: Neonate With Hydronephrosand Prenatally Detectedmentioning

confidence: 99%

“…like localized hydronephrosis, abscess, or cysts. Some authors have solved this problem by using delayed 24-h images (De Maeyer et al 1982). 99mTc-DTPA is largely used in children with a uropathy for the evaluation of the separate left and right glomerular filtration rate (GFR), as well as for the evaluation of both transit time and drainage. All these changes may disappear slowly under adequate treatment, but it is not unusual for them to remain unchanged several months after treatment.…”

mentioning

confidence: 99%

Paediatric nuclear medicine

Piepsz

Gordon

Hahn³

1991

Eur J Nucl Med

View full text Add to dashboard Cite

Until the 1980s no serious attempts were made to develop paediatric nuclear medicine, as for various reasons many centres were reluctant to perform radionuclide examinations on children. Then two books were published on paediatric nuclear medicine in 1984 and 1985, respectively. In 1987, a group of physicians formed an informal club of paediatricians and nuclear medicine specialists in an effort to improve the relationship and cooperation between these specialties. Carrying out nuclear medicine examinations on children requires a completely different approach than on adults. Suggestions are made and tips given, and the specific problems involved are discussed in detail.

show abstract

A Clinical Study of ^99m Technetium Dimercaptosuccinic Acid Uptake in Obstructed Kidneys: Comparison with the Creatinine Clearance

Cited by 20 publications

References 3 publications

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Combination of DMSA-Scintigraphy and Hippuran Renography in Unilateral Obstructive Nephropathy

Paediatric nuclear medicine

Contact Info

Product

Resources

About

A Clinical Study of 99m Technetium Dimercaptosuccinic Acid Uptake in Obstructed Kidneys: Comparison with the Creatinine Clearance

Cited by 20 publications

References 3 publications

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Diagnostic Accuracy of Urinary Creatinine Concentration in the Estimation of Differential Renal Function in Patients with Obstructive Uropathy

Combination of DMSA-Scintigraphy and Hippuran Renography in Unilateral Obstructive Nephropathy

Paediatric nuclear medicine

Contact Info

Product

Resources

About

A Clinical Study of ^99m Technetium Dimercaptosuccinic Acid Uptake in Obstructed Kidneys: Comparison with the Creatinine Clearance