A Clinical Study of Serum Glutamic Oxalacetic Transaminase Isoenzymes in Liver Diseases

Gabrieli, E. R.; Orfanos, Adam P.

doi:10.3181/00379727-128-33128

Cited by 11 publications

(3 citation statements)

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“…AAT II contributed 23.8 % to total AAT activity. This contrasts with the results of Schmidt et al [18] and of Gabrieli and Orfanos [7], who found values of 4.3% and 8%, respectively.…”

Section: Resultscontrasting

confidence: 56%

Aspartate Aminotransferase Isoenzymes in Human Serum in Various Liver Diseases

Idéo¹,

R²,

Bellobuono³

et al. 1971

Enzyme

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“…AAT II contributed 23.8 % to total AAT activity. This contrasts with the results of Schmidt et al [18] and of Gabrieli and Orfanos [7], who found values of 4.3% and 8%, respectively.…”

Section: Resultscontrasting

confidence: 56%

Aspartate Aminotransferase Isoenzymes in Human Serum in Various Liver Diseases

Idéo¹,

R²,

Bellobuono³

et al. 1971

Enzyme

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“…The mean % of mitochondrial isoenzyme for the normal group in the previous report is 25%, a value near the maximum that has ever been reported (7,9,18) and higher than we detected in any individual in any group. This high mean % of mitochondrial ---activity for the normal group suggests that the chromatographic techniaue used in the ~revious studv.…”

Section: Subjects With Serum Ast In the Normal Range This "Normal"mentioning

confidence: 56%

“…Previous studies have shown that visible light significantly reduces serum bilirubin concentrations in infants (7,10). The photochemical reactions responsible for this effect, photodegradation and photoisomerization, occur primarily in exposed skin (6,12).…”

Section: Discussionmentioning

confidence: 99%

The Proportion of Mitochondrial Isoenzyme of Aspartate Aminotransferase Is Not Elevated in Reye's Syndrome

et al. 1983

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SummaryWe reexamined a previously reported, highly specific increase in the relative proportion of the mitochondrial isoenzyme of asparate aminotransferase (AST) in the serum of patients with Reye's Syndrome. Using ion exchange chromatography, we measured mitochondrial, cytosolic, and total AST in serum samples from ( 1 ) 10 patients early in the course of Reye's Syndrome; (2) nine controls with normal serum AST; and (3) seven controls with other diseases causing an increase in serum AST. The mitochondrial percentage (2.8 +. 2.0%) in Reye's Syndrome was significantly lower (P < 0.05) than that of both the normal control group (6.1 2 7.1%) and the group with increased AST (5.6 2 4.0%). We thus failed to confirm the previous report of a specific increase in the % of mitochondrial isoenzyme in Reye's Syndrome, and conclude that the % of mitochondrial isoenzyme is not likely to be a useful marker of (or predictor for progression to) Reye's Syndrome. AbbreviationsAST, aspartate aminotransferase LDH, lactate dehydrogenase MDH, malate dehydrogenase P-5-P, pyridoxal-5'-phosphate

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Aminotransferase (Transaminase) Isoenzymes

Wilkinson

1970

Isoenzymes

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A Clinical Study of Serum Glutamic Oxalacetic Transaminase Isoenzymes in Liver Diseases

Cited by 11 publications

References 0 publications

Aspartate Aminotransferase Isoenzymes in Human Serum in Various Liver Diseases

Aspartate Aminotransferase Isoenzymes in Human Serum in Various Liver Diseases

The Proportion of Mitochondrial Isoenzyme of Aspartate Aminotransferase Is Not Elevated in Reye's Syndrome

Aminotransferase (Transaminase) Isoenzymes

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