A clinical study of prevalence of gestational diabetes mellitus and associated risk factors at a tertiary care centre in Karnataka, India

Shridevi, A S; Prabhudev, Prema; Bhovi, Madhusoodana R.

doi:10.18203/2320-1770.ijrcog20151271

Cited by 5 publications

(3 citation statements)

References 13 publications

(22 reference statements)

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“…In our study, advanced maternal age, high BMI and positive family history of DM had statistically significant association with abnormal GCT which is similar to other studies (6,7,8) where advanced maternal age, high BMI and positive family history of DM had statistically significant association with GDM(p < 0.05).…”

Section: Discussionsupporting

confidence: 91%

Abnormal glucose challenge test in pregnancy: A study at tertiary care hospital

Deshpande,

Gadappa,

Dhaduti

et al. 2017

Int. J. Clin. Obstet. Gynaecol.

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The study was carried out to find out prevalence of abnormal glucose challenge test (GCT), using DIPSI guidelines by using venous as well as capillary glucometer test in pregnant women and also to study the risk factors along with feto-maternal outcome in diagnosed cases of abnormal GCT. Material & Methods:The present longitudinal study was conducted between June 2015 to May 2017 in GMCH, Aurangabad. A total of 700 pregnant women seeking antenatal care between 16-32 weeks gestation were enrolled for study. Selected women were subjected for 75gm oral glucose challenge test. Venous plasma glucose as well as capillary blood glucose values were estimated and compared. Abnormal glucose tolerance was diagnosed on the basis of 2 hour plasma glucose values more than 120 mg/dl. Prevalence of abnormal GCT & risk factors were studied. Women diagnosed and treated as per DIPSI guidelines and followed up for maternal and fetal outcome. Data collected was entered in Microsoft excel and analysed further using SPSS Software version 23 package. Results: Out of 700 antenatal women, 70 women were diagnosed as having abnormal GCT by venous plasma glucose. method. Abnormal GCT was seen in 10% of the screened participants. Statistically Significant association was found between abnormal GCT and age, BMI, gravidity, positive family history, history of previous fetal or early neonatal deaths. Sensitivity of capillary glucometer method was 100% and specificity was 99.68% when compared to venous laboratory method. Out of 70 cases diagnosed as abnormal GCT, 6 lost to follow up. In follow up of 64 women with abnormal GCT, 50 women were treated with medical nutritional therapy and 20 required MNT & insulin. 56 women delivered at term & 8 women had preterm delivery. Conclusion:In low resource settings where Venous plasma glucose is impossible, universal and timely screening of all pregnant women with 75 gm GCT with glucometer should be done to reduce adverse pregnancy outcome and for preventing type 2 DM. Creating awareness regarding risk factors and targeting this population for lifestyle modification is very essential in order to prevent fetal origin of adult onset diseases.

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Section: Discussionsupporting

confidence: 91%

Abnormal glucose challenge test in pregnancy: A study at tertiary care hospital

Deshpande,

Gadappa,

Dhaduti

et al. 2017

Int. J. Clin. Obstet. Gynaecol.

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“…16 Though Al-Rowaily et al found multiparous women were more likely to have GDM than nulliparous women. 17 Like Duman, this study also found high bodymass index and positive family history of diabetes as associated risk factors. In our study we found bad obstetric history and history of macrosomia in previous pregnancy as associated risk factors which is supported by a study done in Karnataka by Shridevi et al 18 The study by Shridevi et al also found a greater prevalence of GDM in women with advanced age, obesity, family h/o DM and past h/o GDM.…”

Section: Discussionsupporting

confidence: 56%

Frequency of gestational diabetes mellitus and associated risk factors amongst women attending antenatal clinic at a tertiary care hospital of West Bengal, India

Rabi,

Bandyopadhyay,

Adak

2023

Int J Reprod Contracept Obstet Gynecol

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Background: Women with gestational diabetes are associated with adverse pregnancy outcomes. This study was conducted to evaluate prevalence of gestational diabetes mellitus and associated risk factors amongst women attending antenatal clinic of a tertiary care hospital of west Bengal, India. Methods: Universal screening for gestational diabetes mellitus was done in 215 women with estimated gestational age between 24 weeks to 28 weeks. They were requested to drink 75 gram of glucose dissolved 300 ml of water irrespective of their last meal. Gestational diabetes mellitus was diagnosed if 2 hour plasma glucose value was ≥ 140 mg/dl. Relevant history was taken and associations with risk factors like age, parity, pregnancy body-mass index, bad obstetric history, family history of diabetes and history of previous macrosomia were analysed statistically. Results: This study found that prevalence of gestational diabetes mellitus was 14.9%.Statistically significant association was found between glucose tolerance in pregnancy and maternal age, pregnancy body-mass-index, bad obstetric history, family history of diabetes and history of previous macrosomia. Conclusions: Prevalence of gestational diabetes mellitus was 14.9% which can be considered alarming and its associations with risk factors were statistically significant.

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“…Fatthy et al [ 22 ] and Shridevi et al [ 23 ] showed that BMI >30 was significantly associated with the risk of developing GDM. There was no statistically significant difference (p=0.633) between the BMI of the two groups in our study.…”

Section: Discussionmentioning

confidence: 99%

An Evaluation of the Second Trimester Thyroid Function Test in Gestational Diabetes Mellitus: A Case-Control Study

Srivastava¹,

P²,

Mondal³

et al. 2023

Cureus

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Introduction: Gestational diabetes mellitus (GDM) is defined as glucose intolerance in a female with its onset or first recognition during pregnancy. Females with GDM are at higher risk of developing antenatal complications like preeclampsia during pregnancy and increased risk of type 2 diabetes as well as cardiovascular disorders later in their life. Maternal thyroid changes in the first and second trimesters of pregnancy have been widely related to the risk of GDM. Hypothyroidism during pregnancy is associated with early and late complications like abortions, anaemia, gestational hypertension, placental abruption and postpartum haemorrhage, impaired infant neurodevelopment, and low birth weight.Objectives: This study aims to compare the thyroid function test (TFT) (serum fT3, fT4, TSH) and thyroid peroxidase antibody (anti TPO) between GDM and non GDM pregnant women in the second trimester and to correlate the adverse pregnancy outcomes with TFT in GDM and non GDM women.

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A clinical study of prevalence of gestational diabetes mellitus and associated risk factors at a tertiary care centre in Karnataka, India

Cited by 5 publications

References 13 publications

Abnormal glucose challenge test in pregnancy: A study at tertiary care hospital

Abnormal glucose challenge test in pregnancy: A study at tertiary care hospital

Frequency of gestational diabetes mellitus and associated risk factors amongst women attending antenatal clinic at a tertiary care hospital of West Bengal, India

An Evaluation of the Second Trimester Thyroid Function Test in Gestational Diabetes Mellitus: A Case-Control Study

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