A Clinical Study of Microvascular Complications in Newly Diagnosed Diabetes Mellitus Patients

Patel, Yash; Shingare, Ashay; Kalita, Gautam; Bhandari, Vinaya

doi:10.15373/2249555x/feb2014/108

Cited by 3 publications

(4 citation statements)

References 3 publications

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“…Raman et al studied 248 newly diagnosed T2DM patients and reported a prevalence of 30.2% in south Indian population [ 11 ]. Studies by Patel et al and Dutta et al reported a prevalence rate of about 30% [ 12 , 13 ]. The present study has reported low prevalence rates when compared to abovementioned studies.…”

Section: Discussionmentioning

confidence: 99%

Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients

Bansal

Gudala

Esam

et al. 2014

International Journal of Chronic Diseases

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The study was aimed at assessing the prevalence of microvascular complications and associated risk factors in newly diagnosed type 2 diabetes mellitus patients. A cross-sectional study was conducted in a public tertiary care hospital. All the recruited patients underwent extensive examination for the presence of microvascular complications like neuropathy, retinopathy, and nephropathy. Prevalence of any complication was 18.04%. Prevalence of neuropathy, retinopathy, and nephropathy was found to be 8.2%, 9.5%, and 2.8%, respectively. Triglycerides (OR, 1.01; P = 0.011) and old age (OR, 1.06; P ≤ 0.01) were significantly associated with any complication. Triglycerides were significantly associated with neuropathy (OR, 1.01; P = 0.05) and retinopathy (OR, 1.01; P = 0.02). Being male posed high risk for nephropathy (OR, 0.06; P = 0.01). These results are suggesting need of regular screening for microvascular complications.

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Section: Discussionmentioning

confidence: 99%

Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients

Bansal

Gudala

Esam

et al. 2014

International Journal of Chronic Diseases

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“…According to the study by Sankara nethralaya, diabetic retinopathy says that 23% of patients are found to be diabetic retinopathy (Raman et al, 2009). According to Xu et al and Yash et al The 19.6% are affected with retinopathy and 24% of patients, respectively (Patel et al, 2011;Xu et al, 1997). [Table 1]…”

Section: Types Of Complicationsmentioning

confidence: 99%

“…When compared to other complications, neuropathy had less prevalence. But according to Yash et al, 36% of patients are prone to diabetic neuropathy and Nambuya, 46% patients are affected with diabetic neuropathy (Patel et al, 2011;Nambuya et al, 1996), [Table 2] The subjects with HbA1C > 7.5% are more prone to microvascular complications when compared to the patients with HbA1C <7.5%. These values may not be statically signi icant (>0.05)…”

Section: Types Of Complicationsmentioning

confidence: 99%

Prevalence of microvascular complications of diabetes mellitus in tertiary care hospital

K¹,

B²,

Bheemamma³

et al. 2020

ijrps

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The major cause of mortality and morbidity in the present generation is diabetes mellitus. The high prevalence of microvascular complications in diabetes mellitus occurs due to the untreated long duration of hyperglycemia. The main aim of the study is assessing the prevalence of microvascular complications of patients who are diagnosed with diabetes mellitus in public tertiary care hospitals. A retro-prospective observational study was conducted in the outpatient department of medicine at a tertiary care hospital. We took the samples of a total of 300 consecutive patients who are diagnosed with diabetes mellitus with microvascular complications were included in the study. To diagnose microvascular complications of diabetes mellitus clinical parameters, patient past and present history and other related investigations were included. A total of 300 patients in this study, 160 are males and 140 are females. The age range was 30-80 years, with a mean age of 49.43±13.45 years. 31% of patients are diagnosed with neuropathy, 35% of patients are diagnosed with retinopathy and 34% of patients are diagnosed with nephropathy. 68.6% of patients are affected with microalbuminuria, whereas 31.3% of patients are affected with macroalbuminuria. [HbA1C] levels are divided into two groups on the basis of glycated hemoglobin levels in subjects. The patients with HbA1C >7.5% are found to 61% and 39% are found to be in the range of HbA1C 6.5-7.5%. By comparing both patients with HbA1C>7.5% are more prone to microvascular complications than that of HbA1C 6.5-7.5%. The 23% subjects had normal BMI [18.5-24.99kg/m2, 55% subjects were over-weight [25-29.99kg/m2 and 21.3% subjects were obese [>30kg/m2]. Early detection and identification of DM may reduce the risk of getting complications. To prevent or retard further progression of these complications, we should control blood sugar levels.

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“…Albuminuria also indicates vascular permeability disorder, which is caused by generalized endothelial dysfunction. [1][2][3] On average, diabetic retinopathy occurs after 8-10 years of DM2. It engages both eyes and leads to blindness in the final stage.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Microvascular Complications in the Early Phase of Diabetes Mellitus Type 2 with Albuminuria

Surkovic¹

2020

South Clin Ist Euras

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Objective: Diabetes Mellitus Type 2 (DM2) is characterized by varying degrees of insulin resistance, impaired insulin secretion, and increased glucose production. Some people with DM2 have more complications such as nephropathy, retinopathy, and neuropathy. The earliest stage of renal impairment occurs with prolonged microalbuminuria. This study aimed to determine the incidence of the most common microvascular complications in DM2 patients. Methods:We retrospectively evaluated the data of 126 patients who had undergone treatment in 2014. It includes anamnesis, laboratory, and physical examination data from the patient histories. All patients with early stage DM2 were separated into two groups based on the presence of albuminuria: Group I -macroalbuminuria and Group II -microalbuminuria (<300 mg). Analysis and statistical processing of the collected data were performed to evaluate microvascular complications and determine the incidence of albuminuria in the studied population. Results:The prevalence of macroalbuminuria was 60.3% (76 patients). In both groups, as in the total sample, the frequency of women was higher (57.9%). The prevalence of macroalbuminuria was strongly influenced by age (≥65 years) of the patients (72.4%, average age = 69.8±11.1 years). Microalbuminuria has been proven to be an extremely significant marker for development of microvascular complications in DM2 (retinopathy 39.5%, neuropathy 52.6%, and nephropathy 54%). Conclusion:Early diagnosis of microvascular complications and an adequate therapeutic approach is needed to prevent disability. Therefore, it is important to introduce the screening for the presence of microalbuminuria in practice, which will identify patients at increased risk of developing microvascular complications.

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A Clinical Study of Microvascular Complications in Newly Diagnosed Diabetes Mellitus Patients

Cited by 3 publications

References 3 publications

Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients

Microvascular Complications and Their Associated Risk Factors in Newly Diagnosed Type 2 Diabetes Mellitus Patients

Prevalence of microvascular complications of diabetes mellitus in tertiary care hospital

Frequency of Microvascular Complications in the Early Phase of Diabetes Mellitus Type 2 with Albuminuria

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