“…Post Google scholar search, 13 additional articles were further added. [28][29][30][31][32][33][34][35][36][37][38][39][40] Also the 2013 paper from Nithyanandam et al 25 was a post-hoc analysis, so we retrieved the data from the primary publication. 41 Data were extracted from the 27 relevant articles for review.…”
Section: Literature Searchmentioning
confidence: 99%
“…18,19,21,33 Eight studies reported exclusively on HZO cases. 16,17,23,32,35,37,38,41 Of the 27 publications, seven 21,22,24,27,28,31,40 provided proportions of HZ cases among all patients who attended outpatient visits in the considered departments, ranging between 0.28 and 2.36% (Figure 1). For example in the study with the largest sample size conducted in a rural hospital in Gujarat, 938 HZ cases were reported between June 2008 and December 2016 among all dermatology outpatients, yielding a proportion of 0.38%.…”
Section: Characteristics Of Included Studiesmentioning
confidence: 99%
“…14,16,19,20,22,24,[28][29][30][31]33,35,37,38,41 Six studies found the ratios to be in the order of 2:1, 15,17,23,26,36,40 Five studies, however, reported more women patients with HZ than men, in the range of 0.6:1 to 0.9:1. 18,21,32,34,39…”
Section: Sex Ratiomentioning
confidence: 99%
“…HIV status of the enrolled population was clearly stated in 23 studies. 14,15,[17][18][19][20][21][22][23][24][26][27][28]31,32,[34][35][36][37][38][39][40][41] For other studies, HIV status was either not assessed or mentioned. The reported frequency of HIV seropositivity among the studied patients varied between 0% 22,27,38 and 44.4%.…”
Section: Predisposing Factors For Hz Diseasementioning
confidence: 99%
“…The reported frequency of HIV seropositivity among the studied patients varied between 0% 22,27,38 and 44.4%. 17 Diabetes mellitus was reported in 15 studies 14,16,20,22,23,[27][28][29]32,[34][35][36][37][38][39] with a percentage range of 0% 27 to 56.3%. 35 The highest proportion of diabetes (56.3%) was reported in a study conducted in the Ophthalmology department of a tertiary hospital in Odisha where 20/32 patients (62.5%) were older than 60 years of age.…”
Section: Predisposing Factors For Hz Diseasementioning
In India, although incidence of Herpes zoster has not been assessed, regional cases have been reported. We revisited the peer-reviewed literature on clinical cases of HZ to depict the trends in population characteristics, disease presentation, and predisposing factors for the disease in India. Systematically conducted literature search yielded 27 studies, published between January 2011 and May 2020, reporting 3124 HZ clinical cases, with high proportions in older adults (>50 years of age: 15.0-81.3%). Thoracic dermatome was consistently reported as the most frequent site affected by HZ (38.9-71.0%). Postherpetic neuralgia and secondary bacterial infections were the two most frequent complications (10.2-54.7% and 3.5-21.0%, respectively). Despite the paucity of data and gaps in the reporting of HZ cases, available evidence indicate that the disease causes an important burden to older adults in India, suggesting that preventive strategies, along with recommendations to healthcare practitioners, can help mitigate the burden of HZ.
“…Post Google scholar search, 13 additional articles were further added. [28][29][30][31][32][33][34][35][36][37][38][39][40] Also the 2013 paper from Nithyanandam et al 25 was a post-hoc analysis, so we retrieved the data from the primary publication. 41 Data were extracted from the 27 relevant articles for review.…”
Section: Literature Searchmentioning
confidence: 99%
“…18,19,21,33 Eight studies reported exclusively on HZO cases. 16,17,23,32,35,37,38,41 Of the 27 publications, seven 21,22,24,27,28,31,40 provided proportions of HZ cases among all patients who attended outpatient visits in the considered departments, ranging between 0.28 and 2.36% (Figure 1). For example in the study with the largest sample size conducted in a rural hospital in Gujarat, 938 HZ cases were reported between June 2008 and December 2016 among all dermatology outpatients, yielding a proportion of 0.38%.…”
Section: Characteristics Of Included Studiesmentioning
confidence: 99%
“…14,16,19,20,22,24,[28][29][30][31]33,35,37,38,41 Six studies found the ratios to be in the order of 2:1, 15,17,23,26,36,40 Five studies, however, reported more women patients with HZ than men, in the range of 0.6:1 to 0.9:1. 18,21,32,34,39…”
Section: Sex Ratiomentioning
confidence: 99%
“…HIV status of the enrolled population was clearly stated in 23 studies. 14,15,[17][18][19][20][21][22][23][24][26][27][28]31,32,[34][35][36][37][38][39][40][41] For other studies, HIV status was either not assessed or mentioned. The reported frequency of HIV seropositivity among the studied patients varied between 0% 22,27,38 and 44.4%.…”
Section: Predisposing Factors For Hz Diseasementioning
confidence: 99%
“…The reported frequency of HIV seropositivity among the studied patients varied between 0% 22,27,38 and 44.4%. 17 Diabetes mellitus was reported in 15 studies 14,16,20,22,23,[27][28][29]32,[34][35][36][37][38][39] with a percentage range of 0% 27 to 56.3%. 35 The highest proportion of diabetes (56.3%) was reported in a study conducted in the Ophthalmology department of a tertiary hospital in Odisha where 20/32 patients (62.5%) were older than 60 years of age.…”
Section: Predisposing Factors For Hz Diseasementioning
In India, although incidence of Herpes zoster has not been assessed, regional cases have been reported. We revisited the peer-reviewed literature on clinical cases of HZ to depict the trends in population characteristics, disease presentation, and predisposing factors for the disease in India. Systematically conducted literature search yielded 27 studies, published between January 2011 and May 2020, reporting 3124 HZ clinical cases, with high proportions in older adults (>50 years of age: 15.0-81.3%). Thoracic dermatome was consistently reported as the most frequent site affected by HZ (38.9-71.0%). Postherpetic neuralgia and secondary bacterial infections were the two most frequent complications (10.2-54.7% and 3.5-21.0%, respectively). Despite the paucity of data and gaps in the reporting of HZ cases, available evidence indicate that the disease causes an important burden to older adults in India, suggesting that preventive strategies, along with recommendations to healthcare practitioners, can help mitigate the burden of HZ.
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