A clinical study of early onset pre-eclampsia v/s late onset pre-eclampsia

Abstract

Introduction: Preeclampsia is a multi-system disorder of unknown etiology that is unique to human pregnancy and is characterized by abnormal vascular response to placentation associated with increased systematic vascular resistance (SVR), enhanced platelet aggregation, activation of coagulation system and endothelial dysfunction. It remains a major cause of maternal and fetal/neonatal morbidity and mortality. Methodology: As per case record form thorough clinical examination including BP, edema, pallor etc was done. Detailed obstetric examination was done in the form of obstetric palpation, presentation, amount of liquor and fetal heart sounds. All the women were investigated (routine and specific for PE), managed according to the hospital protocol, followed up till delivery and maternal and perinatal outcomes were noted. The women once diagnosed as PE they were hospitalized, investigated for PE and they were managed with antihypertensive as per hospital protocol. Results: Mean gestational age in the group 1 was 27.88 ± 4.03374 weeks and mean gestational age in the group 2 was 38.68 ± 1.98402 weeks. Mean gestational age of overall study subjects was 33.28 ± 6.28141 weeks. The association between the two groups was non significant. Conclusion: Family history of PE was noted in 11 out of 100 women in the study and it was noted in 63.6% in early onset preeclampsia group (Group1) as compared to 36.4% in late onset preeclampsia (Group2).

Study of Fetomaternal Outcome in Cases of Pre-Eclampsia

“…Kari Annapurna et al [22] observed 57.6% Caesarean section. In another study 43% delivered by Caesarean section [26]. It is more when compared with other studies by Singh et al (21.4%) [19] and Rathore R, Butt NF et al [27] (15%).…”