A clinical picture of pulmonary embolism revealing light‐chain myeloma

Abstract

Key Clinical MessageWe are highlighting on the particularity of a clinical picture of pulmonary embolism revealing light‐chain myeloma in a 56‐year‐old male patient. Myeloma remains a rare affection. Even though its revelation through pulmonary embolism remains rare, it can be explained by hyperviscosity syndrome accompanying it.

Monoclonal Light Chains in Multiple Myeloma: The Sinister Immunoglobulin

“…The systemic significance of monoclonal light chain-induced vasculitis and thrombotic microangiopathy warrants additional investigation, as generalized vasculitis has the potential to damage other vital organs as well [16,[55][56][57][58][59][60][61][62][63][64]. Uncommon disorders include light chain renal stones, light chain crystal deposition in cornea, skeletal myopathy, pulmonary embolism, acquired cutis laxa, cutaneous light chain deposition disease, cholestasic hepatitis and light chain deposition liver disease [65][66][67][68][69][70].…”