“…Similarly, the lack of apparent clinical or echocardiographic improvement should not be misconstrued as the absence of benefit from BiVp, just as apparent progression of heart failure may not indicate a lack of benefit from contemporary neurohormonal antagonists. The identification of these "favorable non-responders" is crucial to avoid inadvertent termination of an effective treatment, just as identification of adverse responders19 would be important to avoid continued delivery of a harmful intervention to patients.The assessment of LV (reverse) remodeling has dominated the BiVp literature 20,21 . Recent reports have highlighted the relevance of right ventricular function in patients with BiVp.…”