A Clinical Outcomes and Cost Analysis Comparing Photoselective Vaporization of the Prostate to Alternative Minimally Invasive Therapies and Transurethral Prostate Resection for the Treatment of Benign Prostatic Hyperplasia

Abstract

Compared to alternative treatment options photoselective vaporization of the prostate is a clinically efficacious and cost-effective treatment for symptomatic benign prostatic hyperplasia.

The Effect of Transarterial Prostate Embolization in Hormone-induced Benign Prostatic Hyperplasia in Dogs: A Pilot Study

“…Currently, transurethral prostatectomy is accepted as the gold standard for surgical intervention. However, for those patients at high operative risk or those unsuitable for surgery, various minimally invasive treatment modalities have emerged, including laser therapy, cryoablation, and intraprostatic injection of ethanol (5)(6)(7)(8)(9)(10)(11)(12). However, the results of these new modalities are not superior to those of transurethral prostatectomy, and they have their own limitations.…”

Photoselective green-light laser vaporisation vs. TURP for BPH: meta-analysis

“…2,3 Currently, the main treatment options for BPH include pharmacological therapy, such as a-adrenergic blockers and 5a-reductase inhibitors, or surgery, such as transurethral resection of the prostate (TURP), transurethral incision of the prostate and open simple prostatectomy. 4 Although TURP is the current 'gold standard' treatment for moderate-to-severe LUTS secondary to BPH, 5,6 the procedure has some limitations. Several studies 7,8 have demonstrated that the rate of complications following TURP, including transfusions, infections, urethral strictures, sexual dysfunction, urinary incontinence, urinary retention…”

Photoselective vaporization of the prostate. Review of cost implementation to BPH treatment

“…The model included costs of initial treatment, follow-up care, adverse events and re-treatment. 56 Photoselective vaporization resulted in the largest beneficial changes in IPSS score, maximum flow rates and quality of life scores at all time points evaluated, followed by transurethral resection and then interstitial laser coagulation. The largest difference between PVP and TURP was observed for Qmax (% decrease from baseline at 24 months: 221 vs 89%)…”

“…[2][3][4][5][6][7][8][51][52][53][54][55][56] From these studies, only three have prospectively compared the results of the KTP laser prostatectomy to those of TURP or other treatment modalities. [54][55][56] Furthermore, long term results of a 5-year follow-up have been presented in only one study. 2 All these studies showed that KTP laser prostatectomy is a method of high effectiveness, providing the patients with an excellent short and long-term functional outcome, whereas at the same time the method has a low morbidity.…”