A clinical case of Trichophyton menthagrophytes and Microsporum canis co-infection in a Siberian tiger (Panthera tigris altaicа)

Mihaylov, Georgi; Tsachev, И.; Petrov, Vladimir; Marutsov, P.; Zhelev, G.; Koev, K.; Mihaylov, R.

doi:10.15547/bjvm.940

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…Dermatophytoses due to two different dermatophytes are very rarely reported. These mixed dermatophyte infections, rare in humans, on the other hand appear to be well documented in pets, especially dogs and cats according to Mihaylov et al [25].…”

Section: Discussionmentioning

confidence: 97%

Evaluation of the Multiplex Real-Time PCR DermaGenius® Assay for the Detection of Dermatophytes in Hair Samples from Senegal

Ndiaye

Sacheli

Diongue

et al. 2021

JoF

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For the successful treatment of dermatophytoses, especially tinea capitis, there is a need for accurate and rapid diagnostic methods. A lot of recent literature has focused on the detection of dermatophytes directly on sample material such as nails, hair and skin scrapings. Molecular tools offer the ability to rapidly diagnose dermatophytosis within 48 h. This study aimed to compare the results of a commercial real-time PCR (real-time PCR) assay DermaGenius®(DG) 2.0 complete multiplex kit with those of conventional diagnostic methods (direct microscopy and culture). A total of 129 hair samples were collected in Dakar (Senegal) from patients suspected of dermatophytosis. DG was applied for the molecular detection of Candida albicans, Trichophyton rubrum/soudanense, T. interdigitale, T. tonsurans, T. mentagrophytes, T. violaceum, Microsporum canis, M. audouinii, Epidermophyton floccosum, T. benhamiae and T. verrucosum. Dermatophytes species and C. albicans were differentiated by melting curve analysis. The sensitivity and specificity of the PCR assay were 89.3% and 75.3%, respectively. DG PCR was significantly more sensitive than culture (p < 0.001). DG PCR is fast and robust to contamination. In this paper, the main questions discussed were the replacement of culture by a broad-spectrum fungal real-time PCR and the implementation of DG PCR into a routine laboratory in Senegal.

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Section: Discussionmentioning

confidence: 97%

Evaluation of the Multiplex Real-Time PCR DermaGenius® Assay for the Detection of Dermatophytes in Hair Samples from Senegal

Ndiaye

Sacheli

Diongue

et al. 2021

JoF

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“…M. canis, isolated from wild felines, can be identified as the only agent of infection or in combination with T. mentagrophytes (Rotstein et al 1999;Mihaylov et al 2016). Often, other pathogens of dermatomycosis, for example, M. gypseum, are detected from wild animals.…”

Section: Introductionmentioning

confidence: 99%

Generalized Dermatophytosis of Combined Etiology in a Circus Tiger (Panthera Tigris Altaica)

2022

Int J Vet Sci

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There have been few reports on the generalized tinea caused by mixed infection and its treatment. The article describes a case of combined tiger dermatophytosis caused by Microsporum canis and opportunistic skin mycosis associated with mixed aspergillosis infection. The infected hair was affected by fungal elements, confirmed by Wood's lamp and cultural and morphological studies. Cultural and morphological diagnostics were carried out by inoculation of biomaterial on differential Sabouraud media with cycloheximide. The causative agent of classic dermatomycosis Microsporum canis and the causative agents of opportunistic mycoses fungi of the genus Aspergillus were isolated and identified from the affected foci on the skin of a tiger cub. Dermatosis of combined etiology was diagnosed. The preparations were selected and treated for the generalized mycosis of the tiger cub. Itraconazole was effective for treatment. There have been few reports on the generalized tinea caused by mixed infection and its treatment. The article describes a case of combined tiger dermatophytosis caused by Microsporum canis and opportunistic skin mycosis associated with mixed aspergillosis infection. The infected hair was affected by fungal elements, confirmed by Wood's lamp and cultural and morphological studies. Cultural and morphological diagnostics were carried out by inoculation of biomaterial on differential Sabouraud media with cycloheximide. The causative agent of classic dermatomycosis Microsporum canis and the causative agents of opportunistic mycoses fungi of the genus Aspergillus were isolated and identified from the affected foci on the skin of a tiger cub. Dermatosis of combined etiology was diagnosed. The preparations were selected and treated for the generalized mycosis of the tiger cub. Itraconazole was effective for treatment.

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Onyxis de la main à Microsporum langeronii et Trichophyton soudanense révélant une teigne du cuir chevelu à M . langeronii

Diongue

Diop

Diallo

et al. 2016

Journal de Mycologie Médicale

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A clinical case of Trichophyton menthagrophytes and Microsporum canis co-infection in a Siberian tiger (Panthera tigris altaicа)

Cited by 3 publications

References 15 publications

Evaluation of the Multiplex Real-Time PCR DermaGenius® Assay for the Detection of Dermatophytes in Hair Samples from Senegal

Evaluation of the Multiplex Real-Time PCR DermaGenius® Assay for the Detection of Dermatophytes in Hair Samples from Senegal

Generalized Dermatophytosis of Combined Etiology in a Circus Tiger (Panthera Tigris Altaica)

Onyxis de la main à Microsporum langeronii et Trichophyton soudanense révélant une teigne du cuir chevelu à M . langeronii

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