A classification scheme for alternative oxidases reveals the taxonomic distribution and evolutionary history of the enzyme in angiosperms

Costa, José Hélio; McDonald, Allison E.; Arnholdt‐Schmitt, Birgit; Melo, Dirce Fernandes de

doi:10.1016/j.mito.2014.04.007

Cited by 58 publications

(98 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Very recently, a study based on protein phylogenies and sequence harmony method has suggested that AOX1 subfamily has experienced a variable gene expansion with five AOX1 genes (AOX1a, 1b, 1c, 1d, and 1e) generating from one AOX1, which are present in various monocots of angiosperms (Costa et al 2014). Similarily, AOX2 gene expansion was also found in dicots in their study, despite that it is not as widespread as that of monocots.…”

Section: Communicated By Sureshkumar Balasubramanianmentioning

confidence: 53%

“…1). Furthermore, three AOX genes were found in Selaginella moellendorffii, one of which could be differentiated as AOX1d (SM00051G01320) based on the classification scheme proposed by Costa et al (2014) (Costa et al 2014), suggesting that AOX1d might be first present in fern and subsequently entered into angiosperms.…”

Section: Resultsmentioning

confidence: 99%

“…Similarily, AOX2 gene expansion was also found in dicots in their study, despite that it is not as widespread as that of monocots. Intriguingly, AOX2 has to date only been found in eudicot plants, whereas AOX1 members are present in both monocots and eudicots (Considine et al 2002;Vanlerberghe 2013;Costa et al 2014). It is therefore worthwhile to study how AOX2 genes have generated and the extent to which gene duplication has contributed to the evolution of AOX.…”

Section: Communicated By Sureshkumar Balasubramanianmentioning

confidence: 99%

“…The classification of AOX genes in this study is based on the phylogenetic analyses of protein sequences and on classification scheme proposed by Costa et al (2014).…”

Section: Gene Classificationmentioning

confidence: 99%

“…AOX is nonprotonmotive and bypasses ATP-producing site complexes III and IV, thus resulting in the reduction of ATP production and the loss of energy as heat (Vanlerberghe 2013;Moore and Albury 2008). This "energy-wasteful" respiration was originally thought to attract pollinators and be linked to thermogenic plants Meeuse 1975), but we now know that the presence of AOX in nonthermogenic plants is ubiquitous (Costa et al 2014) and the involvement of AOX in responses to all sorts of stress has been well-documented (Vanlerberghe 2013;Vanlerberghe et al 2009). In addition to their roles in plant response to stresses, AOX was also involved in some developmental processes (Pu et al 2015).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Unraveling the evolution and regulation of the alternative oxidase gene family in plants

Lin

2015

Dev Genes Evol

View full text Add to dashboard Cite

Alternative oxidase (AOX) is a diiron carboxylate protein present in all plants examined to date that couples the oxidation of ubiquinol with the reduction of oxygen to water. The predominant structure of AOX genes is four exons interrupted by three introns. In this study, by analyzing the genomic sequences of genes from different plant species, we deduced that intron/exon loss/gain and deletion of fragments are the major mechanisms responsible for the generation and evolution of AOX paralogous genes. Integrating gene duplication and structural information with expression profiles for various AOXs revealed that tandem duplication/block duplication contributed greatly to the generation and maintenance of the AOX gene family. Notably, the expression profiles based on public microarray database showed highly diverse expression patterns among AOX members in different developmental stages and tissues and that both orthologous and paralogous genes did not have the same expression profiles due to their divergence in regulatory regions. Comparative analysis of genes in six plant species under various perturbations indicated a large number of protein kinases, transcription factors and antioxidant enzymes are co-expressed with AOX. Of these, four sets of transcription factors--WRKY, NAC, bZIP and MYB--are likely involved in the regulating the differential responses of AOX1 genes to specific stresses. Furthermore, divergence of AOX1 and AOX2 subfamilies in regulation might be the main reason for their differential stress responses.

show abstract

Section: Communicated By Sureshkumar Balasubramanianmentioning

confidence: 53%

Section: Resultsmentioning

confidence: 99%

Section: Communicated By Sureshkumar Balasubramanianmentioning

confidence: 99%

“…The classification of AOX genes in this study is based on the phylogenetic analyses of protein sequences and on classification scheme proposed by Costa et al (2014).…”

Section: Gene Classificationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Unraveling the evolution and regulation of the alternative oxidase gene family in plants

Lin

2015

Dev Genes Evol

View full text Add to dashboard Cite

show abstract

Variable expression of cyanide detoxification and tolerance genes in cyanogenic and acyanogenic white clover (Trifolium repens)

Kuo,

Small,

Olsen

2023

American J of Botany

View full text Add to dashboard Cite

Premiseβ‐Cyanoalanine synthase (β‐CAS) and alternative oxidase (AOX) play important roles in the ability of plants to detoxify and tolerate hydrogen cyanide (HCN). These functions are critical for all plants because HCN is produced at low levels during basic metabolic processes, and especially for cyanogenic species, which release high levels of HCN following tissue damage. However, expression of β‐CAS and Aox genes has not been examined in cyanogenic species, nor compared between cyanogenic and acyanogenic genotypes within a species.MethodsWe used a natural polymorphism for cyanogenesis in white clover to examine β‐CAS and Aox gene expression in relation to cyanogenesis‐associated HCN exposure. We identified all β‐CAS and Aox gene copies present in the genome, including members of the Aox1, Aox2a, and Aox2d subfamilies previously reported in legumes. Expression levels were compared between cyanogenic and acyanogenic genotypes and between damaged and undamaged leaf tissue.Resultsβ‐CAS and Aox2a expression was differentially elevated in cyanogenic genotypes, and tissue damage was not required to induce this increased expression. Aox2d, in contrast, appeared to be upregulated as a generalized wounding response.ConclusionsThese findings suggest a heightened constitutive role for HCN detoxification (via elevated β‐CAS expression) and HCN‐toxicity mitigation (via elevated Aox2a expression) in plants that are capable of cyanogenesis. As such, freezing‐induced cyanide autotoxicity is unlikely to be the primary selective factor in the evolution of climate‐associated cyanogenesis clines.

show abstract

Do Mitochondria Play a Central Role in Stress-Induced Somatic Embryogenesis?

Arnholdt‐Schmitt

Ragonezi

Cardoso

2016

In Vitro Embryogenesis in Higher Plants

View full text Add to dashboard Cite

This review highlights a four-step rational for the hypothesis that mitochondria play an upstream central role for stress-induced somatic embryogenesis (SE): (1) Initiation of SE is linked to programmed cell death (PCD) (2) Mitochondria are crucially connected to cell death (3) SE is challenged by stress per se (4) Mitochondria are centrally linked to plant stress response and its management. Additionally the review provides a rough perspective for the use of mitochondrial-derived functional marker (FM) candidates to improve SE efficiency. It is proposed to apply SE systems as phenotyping tool for identifying superior genotypes with high general plasticity under severe plant stress conditions.

show abstract

A classification scheme for alternative oxidases reveals the taxonomic distribution and evolutionary history of the enzyme in angiosperms

Cited by 58 publications

References 56 publications

Unraveling the evolution and regulation of the alternative oxidase gene family in plants

Unraveling the evolution and regulation of the alternative oxidase gene family in plants

Variable expression of cyanide detoxification and tolerance genes in cyanogenic and acyanogenic white clover (Trifolium repens)

Do Mitochondria Play a Central Role in Stress-Induced Somatic Embryogenesis?

Contact Info

Product

Resources

About