A chronological database as backbone for clinical practice and research data management

Fearn, Paul; Regan, Kevin; Sculli, Frank; Katz, Jared; Kattan, Michael W.

doi:10.1109/cbms.2003.1212759

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…A key requirement for an effective trial matching tool is access to the most recent patient data by effectively interfacing with existing hospital data management systems. The trial prospector clinical data extractor (CDE) module retrieves patient demography information, primary diagnosis, TNM classification, metastasis status, stage group, and the three most recent laboratory reports in real time from the following existing systems in UHSCC: Caisis Clinical Data Management System: Caisis is an open-source Web-based clinical data management (CDM) system 38 that is used at the UHSCC to store patient demography, disease findings, staging information, and related data across multiple clinical management disease teams. SoftLab Laboratory Information System: SoftLab is a proprietary patient laboratory information management (LIM) system 39 and is used at UHSCC to store all blood-based diagnostic tests ordered by physicians that are performed at any laboratory within the UH health system. The laboratory test results are retrieved from the SoftLab LIM system using an application called Clearview Ace 40 in the CDE module, which complies with the Health Insurance Portability and Accountability Act (HIPAA) data security and privacy regulations implemented in UHSCC. …”

Section: Real-time Extraction and Integration Of Multisource Patient mentioning

confidence: 99%

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Trial Prospector: Matching Patients with Cancer Research Studies Using an Automated and Scalable Approach

et al. 2014

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Cancer is responsible for approximately 7.6 million deaths per year worldwide. A 2012 survey in the United Kingdom found dramatic improvement in survival rates for childhood cancer because of increased participation in clinical trials. Unfortunately, overall patient participation in cancer clinical studies is low. A key logistical barrier to patient and physician participation is the time required for identification of appropriate clinical trials for individual patients. We introduce the Trial Prospector tool that supports end-to-end management of cancer clinical trial recruitment workflow with (a) structured entry of trial eligibility criteria, (b) automated extraction of patient data from multiple sources, (c) a scalable matching algorithm, and (d) interactive user interface (UI) for physicians with both matching results and a detailed explanation of causes for ineligibility of available trials. We report the results from deployment of Trial Prospector at the National Cancer Institute (NCI)-designated Case Comprehensive Cancer Center (Case CCC) with 1,367 clinical trial eligibility evaluations performed with 100% accuracy.

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Section: Real-time Extraction and Integration Of Multisource Patient mentioning

confidence: 99%

“…Caisis Clinical Data Management System: Caisis is an open-source Web-based clinical data management (CDM) system 38 that is used at the UHSCC to store patient demography, disease findings, staging information, and related data across multiple clinical management disease teams.…”

Section: Real-time Extraction and Integration Of Multisource Patient mentioning

confidence: 99%