A Chitosan Matrix as a Photomodulator for Bromelain

Pankova, S. M.; Holyavka, M. G.; Kondrat’ev, M. S.; Vyshkvorkina, Yu. M.; Лукин, А. Н.; Artyukhov, V. G.

doi:10.1134/s1062359022110164

Biol Bull Russ Acad Sci

2022

DOI: 10.1134/s1062359022110164

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A Chitosan Matrix as a Photomodulator for Bromelain

S. M. Pankova

M. G. Holyavka²,

M. S. Kondrat’ev³

et al.

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2024

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Cited by 2 publications

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“…The antibiotic and bromelain molecules' PDB files were prepared and minimalized in Chimera. The PDB ID was 1W0Q for bromelain (Sorokin et al, 2023;Pankovaa et al, 2022). And PubChem CID numbers were 54675776 (Liang et al, 2023), 54680690 (Bharadwaj et al, 2020), and 54675783 (Juhi et al, 2023) for tetracycline, demeclocycline (dimethylchlortetracycline) and minocycline, respectively.…”

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confidence: 99%

Tetrasiklin Antibiyotikleri ve Bromelain Enzimi Arasındaki Etkileşimlerin Kenetleme Araçları Kullanılarak İncelenmesi

AYLAZ

2023

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Bromelain, extracted from the stem of the pineapple, is a complex enzyme used for different purposes. Bromelain supplements are often used to facilitate digestion, improve the circulatory system and relieve arthritis symptoms due to its pain relief. However, in some cases where there is a risk of antibiotic use or bleeding, the use of bromelain or direct consumption of pineapple should be limited. For this purpose, this study was carried out to show the mechanism by which the antibiotic bromelain interaction occurs. Firstly, the bromelain molecule and demeclocycline, minocycline, and tetracycline antibiotics were prepared in the UCSF Chimera visualizing program. The interactions were monitored in the Auto Dock Molecular Modelling Toolkit molecular modeling program. The free binding energies of these interactions were also calculated in Auto Dock. According the molecular modelling results, bromelain and demeclocycline, minocycline, tetracycline antibiotics were interact with hydrogen bonds and hydrophobic interactions. These interactions between bromelain and antibiotics were energetically favorable based on free binding energy calculations.

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confidence: 99%

Tetrasiklin Antibiyotikleri ve Bromelain Enzimi Arasındaki Etkileşimlerin Kenetleme Araçları Kullanılarak İncelenmesi

AYLAZ

2023

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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A review on the immobilization of bromelain

Tacias-Pascacio,

Castañeda-Valbuena,

Tavano

et al. 2024

International Journal of Biological Macromolecules

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A Chitosan Matrix as a Photomodulator for Bromelain

Cited by 2 publications

References 12 publications

Tetrasiklin Antibiyotikleri ve Bromelain Enzimi Arasındaki Etkileşimlerin Kenetleme Araçları Kullanılarak İncelenmesi

Tetrasiklin Antibiyotikleri ve Bromelain Enzimi Arasındaki Etkileşimlerin Kenetleme Araçları Kullanılarak İncelenmesi

A review on the immobilization of bromelain

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